Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPC4 | Q9UBN4 | 2/20 | 0.37 |
| ▸ | TRPC5 | Q9UL62 | 2/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | TRPC1 | P48995 | 1/20 | 0.36 |
| ▸ | P2RX3 | P56373 | 11/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20656213 | 1.00 | TRPC4 (0.37) | TRPC4TRPC5KCNH2TRPC1P2RX3 | |
| SCHEMBL20652949 | 0.95 | PKM (0.39) | TRPC4TRPC5KCNH2TRPC1P2RX3 | |
| SCHEMBL20652976 | 0.95 | PKM (0.39) | TRPC4TRPC5KCNH2TRPC1P2RX3 | |
| SCHEMBL20652832 | 0.95 | PKM (0.39) | TRPC4TRPC5KCNH2TRPC1P2RX3 | |
| SCHEMBL20653036 | 0.95 | ADORA3 (0.40) | TRPC4TRPC5KCNH2TRPC1ADORA3 | |
| SCHEMBL20653037 | 0.95 | ADORA3 (0.40) | TRPC4TRPC5KCNH2TRPC1ADORA3 | |
| SCHEMBL20652764 | 0.95 | ADORA3 (0.40) | TRPC4TRPC5KCNH2TRPC1ADORA3 | |
| SCHEMBL20656215 | 0.93 | P2RX3 (0.36) | P2RX3ADORA3MEN1ALDH1A1TSHR | |
| SCHEMBL20655924 | 0.90 | PKM (0.38) | TRPC4TRPC5KCNH2TRPC1P2RX3 | |
| SCHEMBL20652803 | 0.90 | P2RX3 (0.41) | TRPC4TRPC5KCNH2TRPC1P2RX3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019011802-A1 | NOVEL SUBSTITUTED XANTHINE DERIVATIVES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2019-01-17 | — | — | WO | disclosed |