Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.46 |
| ▸ | CDC7 | O00311 | 2/20 | 0.43 |
| ▸ | DBF4 | Q9UBU7 | 2/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | MMP13 | P45452 | 1/20 | 0.43 |
| ▸ | MMP14 | P50281 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 5/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16883790 | 0.84 | NPC1 (0.53) | NPC1RAB9ADCTPP1CDC7DBF4 | |
| SCHEMBL20656275 | 0.84 | MKNK1 (0.42) | MEN1KMT2APOLBKDM4EALDH1A1 | |
| SCHEMBL29846005 | 0.78 | ALDH1A1 (0.50) | NPC1RAB9ADCTPP1CDC7DBF4 | |
| SCHEMBL25434166 | 0.78 | ALDH1A1 (0.50) | NPC1RAB9ADCTPP1CDC7DBF4 | |
| SCHEMBL20656655 | 0.77 | ALDH1A1 (0.48) | NPC1RAB9ADCTPP1CDC7DBF4 | |
| SCHEMBL16876827 | 0.76 | ALDH1A1 (0.46) | NPC1RAB9ADCTPP1CDC7DBF4 | |
| SCHEMBL2918896 | 0.76 | ALDH1A1 (0.60) | NPC1RAB9AMEN1KMT2ANPSR1 | |
| SCHEMBL12683122 | 0.74 | CYP1A2 (0.39) | NPC1RAB9AMEN1KMT2AKDM4E | |
| SCHEMBL15635699 | 0.73 | ELANE (0.62) | ELANE | |
| SCHEMBL16876864 | 0.72 | ALDH1A1 (0.46) | NPC1RAB9ACDC7DBF4NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10428049-B2 | TRPA1 modulators | ALGOMEDIX, INC. (US) | 2019-10-01 | — | — | US | disclosed |
| US-20190016701-A1 | TRPA1 MODULATORS | ALGOMEDIX, INC. (US) | 2019-01-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10428049-B2 | TRPA1 modulators | TRPA1, TRPV1, TRPV2 | NPC1 709/4885RAB9A 3349/4885DCTPP1 1914/4885 |
| US-20190016701-A1 | TRPA1 MODULATORS | TRPA1, TRPV1, TRPV2 | NPC1 709/4885RAB9A 3349/4885DCTPP1 1914/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.