SCHEMBL25434166

SCHEMBL25434166

CCOC(=O)c1cc(-c2cccnc2)nn1C(C)C

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.50
SMN1; SMN2 Q16637 3/20 0.50
POLB P06746 2/20 0.50
RAB9A P51151 3/20 0.48
NPC1 O15118 2/20 0.48
DCTPP1 Q9H773 1/20 0.47
MMP2 P08253 1/20 0.47
MMP13 P45452 1/20 0.47
MMP14 P50281 1/20 0.47
MAPT P10636 4/20 0.46
KDM4E B2RXH2 3/20 0.46
TDP1 Q9NUW8 2/20 0.45
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44
NFKB1 P19838 1/20 0.44
NFKB2 Q00653 1/20 0.44
RELA Q04206 1/20 0.44
CDC7 O00311 1/20 0.44
DBF4 Q9UBU7 1/20 0.44
HPGD P15428 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29846005 1.00 ALDH1A1 (0.50) ALDH1A1SMN1; SMN2POLBRAB9ANPC1
SCHEMBL25433844 0.88 POLB (0.64) ALDH1A1SMN1; SMN2POLBRAB9AMAPT
SCHEMBL25435732 0.86 ALDH1A1 (0.50) ALDH1A1SMN1; SMN2POLBRAB9AMMP2
SCHEMBL17980301 0.84 SMN1; SMN2 (0.53) ALDH1A1SMN1; SMN2POLBRAB9ANPC1
SCHEMBL30982331 0.84 SMN1; SMN2 (0.53) ALDH1A1SMN1; SMN2POLBRAB9ANPC1
SCHEMBL25433886 0.82 RET (0.46) ALDH1A1MAPTKDM4ELMNACYP3A4
SCHEMBL20656655 0.80 ALDH1A1 (0.48) ALDH1A1SMN1; SMN2POLBRAB9ANPC1
SCHEMBL25435903 0.80 ALDH1A1 (0.54) ALDH1A1SMN1; SMN2POLBRAB9ANPC1
SCHEMBL882358 0.79 SMN1; SMN2 (0.47) ALDH1A1SMN1; SMN2POLBRAB9ANPC1
SCHEMBL20656274 0.78 NPC1 (0.47) ALDH1A1SMN1; SMN2POLBRAB9ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12570675-B2 Boronic acid compounds LG CHEM, LTD. (KR) 2026-03-10 US disclosed
US-20240101579-A1 BORONIC ACID COMPOUNDS LG CHEM, LTD. (KR) 2024-03-28 US disclosed
EP-4242213-A1 BORONIC ACID COMPOUND Lg Chem, Ltd. (KR) 2023-09-13 EP disclosed
CN-116568310-A Boric acid compounds 株式会社LG化学 2023-08-08 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12570675-B2 Boronic acid compounds PSMB6, PSMB3, PSMB2 ALDH1A1 3621/4885SMN1; SMN2 777/4885POLB 2583/4885
US-20240101579-A1 BORONIC ACID COMPOUNDS PSMB11, PSMB1, BACH1 ALDH1A1 2005/4885SMN1; SMN2 213/4885POLB 2634/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.