Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12623927 | 0.87 | CYP19A1 (0.37) | CYP19A1SMYD3ALDH1A1NPC1MAPT | |
| SCHEMBL12623972 | 0.80 | ALDH1A1 (0.47) | ALDH1A1NPC1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL12626337 | 0.75 | LSS (0.40) | CYP19A1ALDH1A1NPC1MAPTRAB9A | |
| SCHEMBL12623892 | 0.74 | LMNA (0.46) | CYP19A1ALDH1A1NPC1MAPTRAB9A | |
| SCHEMBL12621853 | 0.74 | ALDH1A1 (0.48) | CYP19A1ALDH1A1NPC1MAPTRAB9A | |
| SCHEMBL17553231 | 0.73 | LIMK2 (0.39) | CYP19A1ALDH1A1NPC1MAPTRAB9A | |
| SCHEMBL17082812 | 0.72 | L3MBTL1 (0.47) | ALDH1A1L3MBTL1 | |
| SCHEMBL12661216 | 0.70 | DRD2 (0.38) | SMYD3ALDH1A1NPC1MAPTRAB9A | |
| SCHEMBL12623903 | 0.70 | ALDH1A1 (0.45) | CYP19A1ALDH1A1NPC1MAPTRAB9A | |
| SCHEMBL12626325 | 0.69 | LIMK2 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2882428-B1 | A METHOD OF INHIBITING TAU PHOSPHORYLATION | PAIN THERAPEUTICS INC (US) | 2019-01-16 | — | — | EP | disclosed |