Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | MAOA | P21397 | 6/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | EYA3 | Q99504 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | PGAM1 | P18669 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10216424 | 0.84 | KDM4E (0.58) | KDM4EMAOACA12CA9CA1 | |
| SCHEMBL183071 | 0.76 | ALDH2 (0.52) | KDM4EMAOAKCNH2HTTALDH1A1 | |
| SCHEMBL30028309 | 0.76 | ALDH2 (0.52) | KDM4EMAOAKCNH2HTTALDH1A1 | |
| SCHEMBL578354 | 0.76 | KDM4E (0.53) | KDM4EMAOACA12CA9CA1 | |
| SCHEMBL5532851 | 0.75 | KDM4E (0.73) | KDM4EMAOACA12CA9ALDH1A1 | |
| SCHEMBL30153359 | 0.75 | KDM4E (0.73) | KDM4EMAOACA12CA9ALDH1A1 | |
| Hydrochloric Acid SCHEMBL28410509 | 0.74 | KDM4E (0.52) | KDM4EMAOACA12CA9CA1 | |
| SCHEMBL8796189 | 0.74 | L3MBTL1 (0.56) | KDM4EHTTALDH1A1HPGDTSHR | |
| SCHEMBL744133 | 0.73 | KDM4E (0.60) | KDM4ECA12CA9HTTALDH1A1 | |
| SCHEMBL19088878 | 0.73 | KDM4E (0.46) | KDM4EMAOAKCNH2CA12CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3430071-A1 | METHOD FOR PRODUCING POLYETHER CARBONATE POLYOLS | Covestro Deutschland AG (DE) | 2019-01-23 | — | — | EP | disclosed |
| CN-1256334-C | Alkoxycarbonylaminobenzoic acid or alkoxycarbonylaminotetrazolylphenyl derivatives as IP antagonists | HOFFMANN LA ROCHE (CH) | 2006-05-17 | — | — | CN | disclosed |