SCHEMBL20658923

SCHEMBL20658923

OB(O)Oc1cccc2nc3ccccc3nc12

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NQO2 P16083 10/20 0.59
MAPT P10636 6/20 0.50
RAB9A P51151 4/20 0.50
ALDH1A1 P00352 3/20 0.50
KMT2A Q03164 2/20 0.50
GAA P10253 2/20 0.50
NPSR1 Q6W5P4 1/20 0.50
POLB P06746 2/20 0.45
THRB P10828 2/20 0.45
BLM P54132 2/20 0.45
MEN1 O00255 1/20 0.45
CASP6 P55212 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
NPC1 O15118 2/20 0.45
LMNA P02545 1/20 0.45
G6PD P11413 1/20 0.45
PKM P14618 1/20 0.45
KDM4E B2RXH2 1/20 0.41
MAPK1 P28482 1/20 0.41
ATM Q13315 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL182949 0.79 NQO2 (0.66) NQO2MAPTRAB9AALDH1A1KMT2A
SCHEMBL2291623 0.78 NQO2 (0.70) NQO2MAPTRAB9AALDH1A1KMT2A
SCHEMBL1513023 0.75 NQO2 (1.00) NQO2MAPTRAB9AALDH1A1KMT2A
SCHEMBL6213177 0.74 NQO2 (0.59) NQO2MAPTRAB9AALDH1A1KMT2A
SCHEMBL3724125 0.74 NQO2 (0.59) NQO2MAPTRAB9AALDH1A1KMT2A
SCHEMBL30901862 0.74 ALDH1A1 (0.50) NQO2MAPTRAB9AALDH1A1KMT2A
SCHEMBL27818979 0.74 ALDH1A1 (0.50) NQO2MAPTRAB9AALDH1A1KMT2A
Hydrogen Sulfide SCHEMBL28130030 0.73 NQO2 (0.96) NQO2MAPTRAB9AALDH1A1KMT2A
Hydrochloric Acid SCHEMBL28752582 0.73 NQO2 (0.96) NQO2MAPTRAB9AALDH1A1KMT2A
Ammonia Solution, Strong SCHEMBL27633219 0.73 NQO2 (0.96) NQO2MAPTRAB9AALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108440573-B Compound, preparation method and organic light-emitting display device 武汉天马微电子有限公司 2022-05-20 CN disclosed
US-11183643-B2 Nitrogen heterocycle fused ring-indene compound and organic light-emitting display device Shanghai Tianma AM-OLED Co., Ltd. (CN) 2021-11-23 US disclosed
CN-108864042-B Aza-condensed ring indene compound and organic light-emitting display device 上海天马有机发光显示技术有限公司 2020-07-14 CN disclosed
US-20200035929-A1 NITROGEN HETEROCYCLE FUSED RING-INDENE COMPOUND AND ORGANIC LIGHT-EMITTING DISPLAY DEVICE Shanghai Tianma AM-OLED Co., Ltd. (CN) 2020-01-30 US disclosed
US-20190027695-A1 COMPOUND, METHOD FOR PREPARING COMPOUND AND ORGANIC LIGHT EMITTING DISPLAY DEVICE WUHAN TIANMA MICRO-ELECTRONICS CO., LTD. (CN) 2019-01-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200035929-A1 NITROGEN HETEROCYCLE FUSED RING-INDENE COMPOUND AND ORGANIC LIGHT-EMITTING DISPLAY DEVICE C1S, CRY2, CRY1 NQO2 740/4885MAPT 1700/4885RAB9A 1001/4885
US-11183643-B2 Nitrogen heterocycle fused ring-indene compound and organic light-emitting display device C1S, CRY2, CRY1 NQO2 740/4885MAPT 1700/4885RAB9A 1001/4885
US-20190027695-A1 COMPOUND, METHOD FOR PREPARING COMPOUND AND ORGANIC LIGHT EMITTING DISPLAY DEVICE DEPTOR, DRD1, TRPA1 NQO2 4186/4885MAPT 67/4885RAB9A 442/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.