SCHEMBL2066528

SCHEMBL2066528

CCOC(N)(COCCO)OCC

nearest known ligand 0.48

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.48
TSHR P16473 2/20 0.38
MAPK1 P28482 1/20 0.38
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
THRB P10828 1/20 0.34
HTT P42858 1/20 0.34
MAPT P10636 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10725722 0.84 TSHR (0.43) ALDH1A1TSHRMAPK1MEN1KMT2A
SCHEMBL1573621 0.79
SCHEMBL8814067 0.76 ALDH1A1 (0.50) ALDH1A1TSHRMAPK1MEN1KMT2A
SCHEMBL720164 0.76 ALDH1A1 (0.50) ALDH1A1TSHRMAPK1MEN1KMT2A
SCHEMBL28411593 0.74 ALDH1A1 (0.48) ALDH1A1TSHRMAPK1MEN1KMT2A
SCHEMBL5675759 0.73 ALDH1A1 (0.35) ALDH1A1TSHR
SCHEMBL7160487 0.73 ALDH1A1 (0.46) ALDH1A1TSHRMAPK1MEN1KMT2A
SCHEMBL17956064 0.73
SCHEMBL870739 0.72
SCHEMBL28027199 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1866355-B1 PERFLUOROPOLYETHER URETHANE ADDITIVES HAVING (METH)ACRYL GROUPS AND HARDCOATS 3M INNOVATIVE PROPERTIES CO (US) 2017-08-23 EP disclosed
US-8981151-B2 Perfluoropolyether urethane additives having (meth)acryl groups and hard coats 3M INNOVATIVE PROPERTIES COMPANY (US) 2015-03-17 US disclosed
US-20140221689-A1 PERFLUOROPOLYETHER URETHANE ADDITIVES HAVING (METH)ACRYL GROUPS AND HARD COATS 3M INNOVATIVE PROPERTIES COMPANY (US) 2014-08-07 US disclosed
US-8729211-B2 Perfluoropolyether urethane additives having (meth)acryl groups and hard coats 3M INNOVATIVE PROPERTIES COMPANY (US) 2014-05-20 US disclosed
US-20130261280-A1 PERFLUOROPOLYETHER URETHANE ADDITIVES HAVING (METH)ACRYL GROUPS AND HARD COATS 3M INNOVATIVE PROPERTIES CO (US) 2013-10-03 US disclosed
US-8476398-B2 Perfluoropolyether urethane additives having (meth)acryl groups and hard coats 3M INNOVATIVE PROPERTIES COMPANY (US) 2013-07-02 US disclosed
US-20120142883-A1 PERFLUOROPOLYETHER URETHANE ADDITIVES HAVING (METH)ACRYL GROUPS AND HARD COATS KLUN THOMAS P (US) 2012-06-07 US disclosed
US-8147966-B2 Perfluoropolyether urethane additives having (meth)acryl groups and hard coats 3M INNOVATIVE PROPERTIES COMPANY (US) 2012-04-03 US disclosed
US-20100160595-A1 PERFLUOROPOLYETHER URETHANE ADDITIVES HAVING (METH)ACRYL GROUPS AND HARD COATS 3M INNOVATIVE PROPERTIES COMPANY 2010-06-24 US disclosed
US-7718264-B2 surface layer is a reaction product of a non-fluorinated crosslinking agent, and a perfluoropolyether urethane having a perfluoropolyether group and a terminal group having at least two (meth)acryl groups; suface modified silica particles 3M INNOVATIVE PROPERTIES COMPANY (US) 2010-05-18 US disclosed
EP-1866355-A1 PERFLUOROPOLYETHER URETHANE ADDITIVES HAVING (METH)ACRYL GROUPS AND HARDCOATS 3M Innovative Properties Company (US) 2007-12-19 EP disclosed
US-20060216500-A1 surface layer is a reaction product of a non-fluorinated crosslinking agent, and a perfluoropolyether urethane having a perfluoropolyether group and a terminal group having at least two (meth)acryl groups; suface modified silica particles 3M INNOVATIVE PROPERTIES COMPANY 2006-09-28 US disclosed
WO-2006102383-A1 PERFLUOROPOLYETHER URETHANE ADDITIVES HAVING (METH)ACRYL GROUPS AND HARDCOATS 3M INNOVATIVE PROPERTIES COMPANY (US) 2006-09-28 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140221689-A1 PERFLUOROPOLYETHER URETHANE ADDITIVES HAVING (METH)ACRYL GROUPS AND HARD COATS FUS, FLNA, ACR ALDH1A1 1139/4885TSHR 2207/4885MAPK1 3570/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.