Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | ERN1 | O75460 | 3/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.35 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 3/20 | 0.33 |
| ▸ | CA2 | P00918 | 3/20 | 0.33 |
| ▸ | CA12 | O43570 | 2/20 | 0.33 |
| ▸ | CA7 | P43166 | 2/20 | 0.33 |
| ▸ | CA9 | Q16790 | 2/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.33 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.33 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30355310 | 0.88 | ALDH1A1 (0.46) | ALDH1A1TDP1POLBL3MBTL1ALOX15 | |
| SCHEMBL1646544 | 0.88 | ALDH1A1 (0.46) | ALDH1A1TDP1POLBL3MBTL1ALOX15 | |
| SCHEMBL21091588 | 0.78 | ALDH1A1 (0.50) | ALDH1A1TDP1POLBL3MBTL1ALOX15 | |
| SCHEMBL617135 | 0.75 | ALDH1A1 (0.48) | ALDH1A1ALOX15AKR1C3CA1CA2 | |
| SCHEMBL21003172 | 0.75 | FOLH1 (0.55) | ALDH1A1TDP1POLBL3MBTL1ALOX15 | |
| SCHEMBL711798 | 0.74 | ALDH1A1 (0.63) | ALDH1A1POLBALOX15AKR1C3CA1 | |
| SCHEMBL23288 | 0.74 | ALDH1A1 (0.63) | ALDH1A1POLBALOX15AKR1C3CA1 | |
| Hydrochloric Acid SCHEMBL9401868 | 0.73 | ALDH1A1 (0.46) | ALDH1A1ALOX15AKR1C3CA1CA2 | |
| SCHEMBL1535448 | 0.72 | ALDH1A1 (0.60) | ALDH1A1POLBALOX15AKR1C3CA1 | |
| Hydrochloric Acid SCHEMBL3459326 | 0.72 | ALDH1A1 (0.60) | ALDH1A1POLBALOX15AKR1C3CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10562875-B2 | Aromatic compounds from furanics | NEDERLANDSE ORGANISAITE VOOR TOEGEPAST-NATUURWETENSCHAPPELIJK ONDERZOEK TNO (NL) | 2020-02-18 | — | — | US | disclosed |
| US-20190023678-A1 | AROMATIC COMPOUNDS FROM FURANICS | NEDERLANDSE ORGANISATIE VOOR TOEGEPAST-NATUURWETENSCHAPPELIJK ONDERZOEK TNO (NL) | 2019-01-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190023678-A1 | AROMATIC COMPOUNDS FROM FURANICS | PAH, AOX1, TYR | ALDH1A1 180/4885TDP1 1783/4885POLB 2956/4885 |
| US-10562875-B2 | Aromatic compounds from furanics | PAH, AOX1, TYR | ALDH1A1 180/4885TDP1 1783/4885POLB 2956/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.