Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 6/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20669397 | 0.86 | HPGD (0.48) | HPGDEPHX2GPR119NAMPTEPHX1 | |
| SCHEMBL26699680 | 0.85 | GPR119 (0.43) | HPGDEPHX2GPR119NAMPTEPHX1 | |
| SCHEMBL20669370 | 0.84 | HPGD (0.50) | HPGDEPHX2GPR119NAMPTEPHX1 | |
| SCHEMBL7810403 | 0.83 | CHRM2 (0.45) | HPGDEPHX2GPR119EPHX1CHRM2 | |
| SCHEMBL31209794 | 0.81 | HPGD (0.46) | HPGDGPR119EPHX1CHRM2CHRM1 | |
| SCHEMBL31208822 | 0.81 | HPGD (0.46) | HPGDGPR119EPHX1CHRM2CHRM1 | |
| SCHEMBL1474868 | 0.80 | USP2 (0.49) | HPGDEPHX2GPR119NAMPTEPHX1 | |
| SCHEMBL29059015 | 0.78 | HSD17B10 (0.46) | HPGDEPHX2GPR119NAMPTEPHX1 | |
| SCHEMBL25366279 | 0.77 | USP2 (0.59) | HPGDEPHX2GPR119NAMPTHRH3 | |
| SCHEMBL20669374 | 0.77 | GPR119 (0.43) | HPGDEPHX2GPR119NAMPTEPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023097031-A1 | BRM TARGETING COMPOUNDS AND ASSOCIATED METHODS OF USE | ARVINAS OPERATIONS, INC. (US) | 2023-06-01 | — | — | WO | disclosed |