Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 4/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.32 |
| ▸ | PAOX | Q6QHF9 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | TERT | O14746 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24596139 | 0.82 | ALDH1A1 (0.38) | TP53SMN1; SMN2ALDH1A1HPGDKMT2A | |
| SCHEMBL21888407 | 0.82 | GABRR1 (0.50) | TP53SMN1; SMN2ALDH1A1GABRR1HPGD | |
| SCHEMBL22929128 | 0.82 | TP53 (0.37) | TP53SMN1; SMN2ALDH1A1GABRR1HPGD | |
| SCHEMBL4505848 | 0.81 | SMN1; SMN2 (0.52) | TP53SMN1; SMN2ALDH1A1GABRR1HPGD | |
| SCHEMBL9795280 | 0.79 | ALDH1A1 (0.47) | TP53SMN1; SMN2ALDH1A1GABRR1HPGD | |
| SCHEMBL14952738 | 0.78 | CYP2D6 (0.46) | SMN1; SMN2ALDH1A1HPGDKMT2ACYP2C19 | |
| SCHEMBL25574095 | 0.76 | CA1 (0.41) | TP53SMN1; SMN2ALDH1A1GABRR1HPGD | |
| SCHEMBL19116288 | 0.73 | ECE1 (0.39) | TP53SMN1; SMN2ALDH1A1GABRR1HPGD | |
| SCHEMBL14518701 | 0.73 | GGPS1 (0.38) | TP53SMN1; SMN2ALDH1A1GABRR1KMT2A | |
| SCHEMBL20644789 | 0.72 | ALDH1A1 (0.44) | SMN1; SMN2ALDH1A1GABRR1PDK2PAOX |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11224661-B2 | Controlled-release CNP agonists with increased NEP stability | ASCENDIS PHARMA GROWTH DISORDERS A/S (DK) | 2022-01-18 | — | — | US | disclosed |
| US-20190022237-A1 | CONTROLLED-RELEASE CNP AGONISTS WITH INCREASED NEP STABILITY | ASCENDIS PHARMA GROWTH DISORDERS A/S (DK) | 2019-01-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190022237-A1 | CONTROLLED-RELEASE CNP AGONISTS WITH INCREASED NEP STABILITY | CNP, NPR1, NPPA | TP53 4679/4885SMN1; SMN2 140/4885ALDH1A1 3005/4885 |
| US-11224661-B2 | Controlled-release CNP agonists with increased NEP stability | CNP, NPR1, NPPA | TP53 4679/4885SMN1; SMN2 140/4885ALDH1A1 3005/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.