Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 10/20 | 0.78 |
| ▸ | PTPN2 | P17706 | 5/20 | 0.78 |
| ▸ | PTPN6 | P29350 | 5/20 | 0.78 |
| ▸ | PTPN11 | Q06124 | 4/20 | 0.78 |
| ▸ | PGK1 | P00558 | 2/20 | 0.58 |
| ▸ | PGK2 | P07205 | 2/20 | 0.58 |
| ▸ | FDPS | P14324 | 2/20 | 0.56 |
| ▸ | PTPRB | P23467 | 3/20 | 0.53 |
| ▸ | PTPRC | P08575 | 2/20 | 0.53 |
| ▸ | CDC25A | P30304 | 1/20 | 0.53 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.49 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.49 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.49 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.49 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4316970 | 0.88 | PTPN1 (1.00) | PTPN1PTPN2PTPN6PTPN11PGK1 | |
| SCHEMBL19696718 | 0.82 | PTPN1 (0.81) | PTPN1PTPN2PTPN6PTPN11PGK1 | |
| SCHEMBL5163589 | 0.80 | PGK1 (0.67) | PTPN1PTPN2PTPN6PTPN11PGK1 | |
| SCHEMBL19696719 | 0.79 | PTPN1 (0.70) | PTPN1PTPN2PTPN6PTPN11PGK1 | |
| SCHEMBL6664712 | 0.78 | PTPN1 (0.79) | PTPN1PTPN2PTPN6PTPN11PGK1 | |
| SCHEMBL3736057 | 0.77 | PTPN1 (0.62) | PTPN1PTPN2PTPN6PTPN11PGK1 | |
| SCHEMBL4316972 | 0.76 | PTPN1 (0.74) | PTPN1PTPN2PTPN6PTPN11PGK1 | |
| SCHEMBL330067 | 0.75 | PTPN1 (0.70) | PTPN1PTPN2PTPN6PTPN11PGK1 | |
| SCHEMBL7535721 | 0.74 | PGK1 (0.69) | PTPN1PTPN2PTPN6PTPN11PGK1 | |
| SCHEMBL13372416 | 0.74 | PTPN1 (0.62) | PTPN1PTPN2PTPN6PTPN11PGK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190024261-A1 | COMPARTMENTALISED COMBINATORIAL CHEMISTRY BY MICROFLUIDIC CONTROL | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2019-01-24 | — | — | US | disclosed |