SCHEMBL4316970

SCHEMBL4316970

O=P(O)(O)C(F)(F)c1ccc(CCCCc2ccc(C(F)(F)P(=O)(O)O)cc2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 14/20 1.00
PTPN2 P17706 5/20 1.00
PTPN6 P29350 5/20 1.00
PTPN11 Q06124 4/20 1.00
PGK1 P00558 3/20 0.69
PGK2 P07205 3/20 0.69
PTPRB P23467 3/20 0.60
PTPRC P08575 2/20 0.60
CDC25A P30304 1/20 0.60
PTPN5 P54829 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19696718 0.90 PTPN1 (0.81) PTPN1PTPN2PTPN6PTPN11PGK1
SCHEMBL6664712 0.89 PTPN1 (0.79) PTPN1PTPN2PTPN6PTPN11PGK1
SCHEMBL20672233 0.88 PTPN1 (0.78) PTPN1PTPN2PTPN6PTPN11PGK1
SCHEMBL4316972 0.86 PTPN1 (0.74) PTPN1PTPN2PTPN6PTPN11PGK1
SCHEMBL330067 0.82 PTPN1 (0.70) PTPN1PTPN2PTPN6PTPN11PGK1
SCHEMBL19696719 0.82 PTPN1 (0.70) PTPN1PTPN2PTPN6PTPN11PGK1
SCHEMBL7535721 0.81 PGK1 (0.69) PTPN1PTPN2PTPN6PTPN11PGK1
SCHEMBL19696720 0.81 PTPN1 (0.66) PTPN1PTPN2PTPN6PTPN11PGK1
SCHEMBL19996618 0.80 PTPN1 (0.66) PTPN1PTPN2PTPN6PTPN11PGK1
SCHEMBL7166929 0.80 PTPN1 (0.64) PTPN1PTPN2PTPN6PTPN11PGK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11573224-B2 Methods of detection using X-ray fluorescence ICAGEN, LLC (US) 2023-02-07 US disclosed
US-20210254056-A1 IDENTIFICATION AND TARGETED MODULATION OF GENE SIGNALING NETWORKS CAMP4 THERAPEUTICS CORPORATION 2021-08-19 US disclosed
US-10877035-B2 Advanced drug development and manufacturing ICAGEN, LLC (US) 2020-12-29 US disclosed
US-20200278346-A1 METHODS OF DETECTION USING X-RAY FLUORESCENCE ADJACENT ACQUISITION CO., LLC 2020-09-03 US disclosed
US-20190192691-A1 REGULATED BIOCIRCUIT SYSTEMS OBSIDIAN THERAPEUTICS, INC. 2019-06-27 US disclosed
US-20150309021-A1 Advanced Drug Development and Manufacturing LOS ALAMOS NATIONAL SECURITY, LLC 2015-10-29 US disclosed
EP-2511844-B1 X-ray microscope XRPRO SCIENCES INC (US) 2015-08-12 EP disclosed
EP-2084519-B1 X-RAY FLUORESCENCE ANALYSIS METHOD LOS ALAMOS NAT SECURITY LLC (US) 2012-08-01 EP disclosed
EP-2084519-A2 ADVANCED DRUG DEVELOPMENT AND MANUFACTURING Los Alamos National Security, LLC (US) 2009-08-05 EP disclosed
WO-2008127291-A2 ADVANCED DRUG DEVELOPMENT AND MANUFACTURING LOS ALAMOS NATIONAL SECURITY, LLC (US) 2008-10-23 WO disclosed
US-20080220441-A1 Advanced drug development and manufacturing THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2008-09-11 US disclosed