Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 10/20 | 0.70 |
| ▸ | PTPN2 | P17706 | 4/20 | 0.70 |
| ▸ | PTPN6 | P29350 | 4/20 | 0.70 |
| ▸ | PTPN11 | Q06124 | 3/20 | 0.70 |
| ▸ | PGK1 | P00558 | 2/20 | 0.60 |
| ▸ | PGK2 | P07205 | 2/20 | 0.60 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.55 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.54 |
| ▸ | PTPRC | P08575 | 2/20 | 0.54 |
| ▸ | PTPRB | P23467 | 2/20 | 0.54 |
| ▸ | CDC25A | P30304 | 1/20 | 0.54 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL823234 | 0.87 | PTPN1 (0.53) | PTPN1PTPN2PTPN6PTPN11PGK1 | |
| SCHEMBL19996618 | 0.84 | PTPN1 (0.66) | PTPN1PTPN2PTPN6PTPN11PGK1 | |
| SCHEMBL3385203 | 0.83 | PTPN1 (0.66) | PTPN1PTPN2PTPN6PTPN11PGK1 | |
| SCHEMBL4316970 | 0.82 | PTPN1 (1.00) | PTPN1PTPN2PTPN6PTPN11PGK1 | |
| SCHEMBL13372416 | 0.81 | PTPN1 (0.62) | PTPN1PTPN2PTPN6PTPN11PGK1 | |
| SCHEMBL117230 | 0.80 | FFAR1 (0.73) | FFAR1KEAP1 | |
| SCHEMBL7831965 | 0.80 | PTPN1 (0.75) | PTPN1PTPN2PTPN6PTPN11PGK1 | |
| SCHEMBL3740693 | 0.79 | FFAR1 (0.46) | PTPN1PTPN2PTPN6PTPN11FFAR1 | |
| SCHEMBL4955219 | 0.78 | NR1H4 (0.52) | PTPN1PTPN2PTPN6PTPN11FFAR1 | |
| SCHEMBL6949855 | 0.78 | PTPN1 (0.59) | PTPN1PTPN2PTPN6PTPN11PGK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 70 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11821109-B2 | Compartmentalised combinatorial chemistry by microfluidic control | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2023-11-21 | — | — | US | disclosed |
| US-20230366125-A1 | COMPARTMENTALISED COMBINATORIAL CHEMISTRY BY MICROFLUIDIC CONTROL | UNITED KINGDOM RESEARCH AND INNOVATION (GB) | 2023-11-16 | — | — | US | disclosed |
| US-20200333334-A1 | COMPARTMENTALISED SCREENING BY MICROFLUIDIC CONTROL | MEDICAL RESEARCH COUNCIL (GB) | 2020-10-22 | — | — | US | disclosed |
| US-10705078-B2 | Compartmentalised screening by microfluidic control | UNITED KINGDOM RESEARCH AND INNOVATION (GB) | 2020-07-07 | — | — | US | disclosed |
| US-20190317085-A1 | COMPARTMENTALISED SCREENING BY MICROFLUIDIC CONTROL | PRESIDENT AND FELLOWS OF HARVARD COLLEGE | 2019-10-17 | — | — | US | disclosed |
| EP-3527978-A2 | COMPARTMENTALISED SCREENING BY MICROFLUIDIC CONTROL | United Kingdom Research and Innovation (GB) | 2019-08-21 | — | — | EP | disclosed |
| EP-3527978-A2 | COMPARTMENTALISED SCREENING BY MICROFLUIDIC CONTROL | United Kingdom Research and Innovation (GB) | 2019-08-21 | — | — | EP | disclosed |
| EP-3524344-A1 | METHOD OF SYNTHESIS AND TESTING OF COMBINATORIAL LIBRARIES USING MICROCAPSULES | United Kingdom Research and Innovation (GB) | 2019-08-14 | — | — | EP | disclosed |
| US-10371699-B2 | Compartmentalised screening by microfluidic control | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2019-08-06 | — | — | US | disclosed |
| US-10371699-B2 | Compartmentalised screening by microfluidic control | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2019-08-06 | — | — | US | disclosed |
| US-20060154298-A1 | Method of synthesis and testing of combinatorial libraries using microcapsules | MEDICAL RESEARCH COUNCIL | 2006-07-13 | — | — | US | disclosed |
| US-20060153924-A1 | Selection by compartmentalised screening | MEDICAL RESEARCH COUNCIL | 2006-07-13 | — | — | US | disclosed |
| WO-2006040554-A1 | COMPARTMENTALISED COMBINATORIAL CHEMISTRY BY MICROFLUIDIC CONTROL | MEDICAL RESEARCH COUNCIL (GB) | 2006-04-20 | — | — | WO | disclosed |
| WO-2006040551-A2 | COMPARTMENTALISED SCREENING BY MICROFLUIDIC CONTROL | MEDICAL RESEARCH COUNCIL (GB) | 2006-04-20 | — | — | WO | disclosed |
| US-20060078893-A1 | Compartmentalised combinatorial chemistry by microfluidic control | MEDICAL RESEARCH COUNCIL | 2006-04-13 | — | — | US | disclosed |
| EP-1608976-A1 | SELECTION BY COMPARTMENTALISED SCREENING | Medical Research Council (GB) | 2005-12-28 | — | — | EP | disclosed |
| EP-1606049-A1 | METHOD OF SYNTHESIS AND TESTING OF COMBINATORIAL LIBRARIES USING MICROCAPSULES | Medical Research Council (GB) | 2005-12-21 | — | — | EP | disclosed |
| US-20050221339-A1 | Compartmentalised screening by microfluidic control | MEDICAL RESEARCH COUNCIL HARVARD UNIVERSITY | 2005-10-06 | — | — | US | disclosed |
| WO-2004088314-A1 | SELECTION BY COMPARTMENTALISED SCREENING | MEDICAL RESEARCH COUNCIL (GB) | 2004-10-14 | — | — | WO | disclosed |
| WO-2004087308-A1 | METHOD OF SYNTHESIS AND TESTING OF COMBINATORIAL LIBRARIES USING MICROCAPSULES | MEDICAL RESEARCH COUNCIL (GB) | 2004-10-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11821109-B2 | Compartmentalised combinatorial chemistry by microfluidic control | STUB1, ACACB, MCCC2 | PTPN1 1858/4885PTPN2 1281/4885PTPN6 1592/4885 |
| US-20230366125-A1 | COMPARTMENTALISED COMBINATORIAL CHEMISTRY BY MICROFLUIDIC CONTROL | STUB1, ACACB, MCCC2 | PTPN1 1858/4885PTPN2 1281/4885PTPN6 1592/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.