SCHEMBL20674

SCHEMBL20674

C=C(C)C(=O)OP(=O)(O)OCC(O)CO

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.38
TSHR P16473 1/20 0.37
SELP P16109 1/20 0.34
BTN3A1 O00481 1/20 0.33
ALDH1A1 P00352 2/20 0.31
KDM4E B2RXH2 1/20 0.31
DUSP3 P51452 1/20 0.31
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
LMNA P02545 1/20 0.31
P2RY10 O00398 3/20 0.31
GPR174 Q9BXC1 3/20 0.31
GPR34 Q9UPC5 2/20 0.31
LPAR6 P43657 1/20 0.31
LPAR1 Q92633 1/20 0.31
LPAR4 Q99677 1/20 0.31
LPAR5 Q9H1C0 1/20 0.31
LPAR2 Q9HBW0 1/20 0.31
LPAR3 Q9UBY5 1/20 0.31
ENPP2 Q13822 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27176150 0.88 BTN3A1 (0.36) SMN1; SMN2TSHRSELPBTN3A1
SCHEMBL2567287 0.86 TSHR (0.36) TSHRALDH1A1P2RY10GPR174GPR34
SCHEMBL28496736 0.85 SMN1; SMN2 (0.39) SMN1; SMN2TSHRALDH1A1KDM4EDUSP3
SCHEMBL28345358 0.85 TSHR (0.40) TSHRBTN3A1ALDH1A1PGK1PGK2
SCHEMBL21953 0.83 SMN1; SMN2 (0.37) SMN1; SMN2SELPKDM4EDUSP3MEN1
SCHEMBL27651385 0.81 SMN1; SMN2 (0.41) SMN1; SMN2SELPKDM4EDUSP3MEN1
SCHEMBL28451789 0.80 PLA2G2A (0.46) TSHRP2RY10GPR174GPR34LPAR6
SCHEMBL1300485 0.80 BTN3A1 (0.41) TSHRBTN3A1ALDH1A1
SCHEMBL28864519 0.79 SMN1; SMN2 (0.43) SMN1; SMN2SELPKDM4EDUSP3MEN1
SCHEMBL2567133 0.79 ALDH1A1 (0.38) TSHRBTN3A1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 477 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4035647-B1 TWO-COMPONENT SELF-ADHESIVE DENTAL COMPOSITION, PROCESS OF PRODUCTION AND USE THEREOF 3M INNOVATIVE PROPERTIES COMPANY (US) 2023-10-18 EP claimed
EP-4035647-A1 TWO-COMPONENT SELF-ADHESIVE DENTAL COMPOSITION, PROCESS OF PRODUCTION AND USE THEREOF 3M Innovative Properties Company (US) 2022-08-03 EP claimed
EP-4056144-B1 DENTAL ARTICLES, METHODS, AND KITS INCLUDING A COMPRESSIBLE MATERIAL SOLVENTUM INTELLECTUAL PROPERTIES COMPANY (US) 2024-07-10 EP disclosed
US-20240216228-A1 CALCIUM AND FLUORINE IONS RELEASING DENTAL COMPOSITION SOLVENTUM INTELLECTUAL PROPERTIES COMPANY 2024-07-04 US disclosed
WO-2024134298-A1 CURABLE PRECURSOR OF A COMPOSITION 3M INNOVATIVE PROPERTIES COMPANY (US) 2024-06-27 WO disclosed
EP-4389788-A1 CURABLE PRECURSOR OF A COMPOSITION 3M Innovative Properties Company (US) 2024-06-26 EP disclosed
US-20240199783-A1 CURABLE PRECURSOR OF AN ADHESIVE COMPOSITION 3M INNOVATIVE PROPERTIES COMPANY 2024-06-20 US disclosed
US-20240189196-A1 INITIATOR SYSTEM WITH POLYMERIZABLE THIOUREA COMPONENT, DENTAL COMPOSITION AND USE THEREOF SOLVENTUM INTELLECTUAL PROPERTIES COMPANY 2024-06-13 US disclosed
WO-2024121658-A1 SURFACE-TREATED FILLER, DENTAL COMPOSITION CONTAINING SUCH A FILLER, PROCESS OF PRODUCTION AND USE THEREOF SOLVENTUM INTELLECTUAL PROPERTIES COMPANY (US) 2024-06-13 WO disclosed
US-11998417-B2 Process for producing a surface-modified dental article SOLVENTUM INTELLECTUAL PROPERTIES COMPANY (US) 2024-06-04 US disclosed
EP-4362881-A1 DENTAL CEMENT COMPOSITION, KIT OF PARTS AND USE THEREOF 3M Innovative Properties Company (US) 2024-05-08 EP disclosed
EP-1578377-A1 COMPOSITIONS INCLUDING POLYMERIZABLE BISPHOSPHONIC ACIDS AND METHODS 3M Innovative Properties Company (US) 2005-09-28 EP disclosed
US-20050175965-A1 Self-etching dental compositions and methods 3M DEUTSCHLAND GMBH (DE) 2005-08-11 US disclosed
US-20050176844-A1 Self-etching emulsion dental compositions and methods 3M DEUTSCHLAND GMBH (DE) 2005-08-11 US disclosed
US-20050175966-A1 Self-adhesive dental compositions and methods 3M DEUTSCHLAND GMBH (DE) 2005-08-11 US disclosed
WO-2005034884-A1 DENTAL COMPOSITIONS AND METHODS WITH ARYLSULFINATE SALTS 3M INNOVATIVE PROPERTIES COMPANY (US) 2005-04-21 WO disclosed
US-20050070627-A1 Dental compositions and methods with arylsulfinate salts 3M INNOVATIVE PROPERTIES COMPANY 2005-03-31 US disclosed
WO-2005018581-A2 SELF-ETCHING DENTAL COMPOSITIONS AND METHODS 3M INNOVATIVE PROPERTIES COMPANY (US) 2005-03-03 WO disclosed
US-20040206932-A1 Compositions including polymerizable bisphosphonic acids and methods 3M INNOVATIVE PROPERTIES COMPANY 2004-10-21 US disclosed
WO-2004060327-A1 COMPOSITIONS INCLUDING POLYMERIZABLE BISPHOSPHONIC ACIDS AND METHODS 3M INNOVATIVE PROPERTIES COMPANY (US) 2004-07-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240216228-A1 CALCIUM AND FLUORINE IONS RELEASING DENTAL COMPOSITION ORAI1, CA3, CHERP SMN1; SMN2 3140/4885TSHR 2815/4885SELP 4216/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.