SCHEMBL2067923

SCHEMBL2067923

CCCc1ccc2nc(C(N)=O)c(S(N)(=O)=O)n2n1

nearest known ligand 0.33

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
PDE10A Q9Y233 2/20 0.33
CA2 P00918 3/20 0.32
CA12 O43570 2/20 0.32
CA1 P00915 2/20 0.32
CA6 P23280 2/20 0.32
CA7 P43166 2/20 0.32
CA13 Q8N1Q1 2/20 0.32
FYN P06241 1/20 0.30
GRK5 P34947 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2067668 0.89 PDE10A (0.33) PDE10A
SCHEMBL2068560 0.86 PDE4A (0.43) CA2CA12CA1
SCHEMBL2066226 0.82 CA2 (0.34) PDE10ACA2CA1
SCHEMBL2066413 0.82 PDE10A (0.38) PDE10ACA2CA12CA1
SCHEMBL2065746 0.81 PDE10A (0.37) PDE10ACA2CA12CA1CA6
SCHEMBL2065950 0.81 CA2 (0.33) PDE10ACA2CA1
SCHEMBL2066797 0.81 CA2 (0.33) PDE10ACA2
SCHEMBL2066698 0.81 CA2 (0.33) PDE10ACA2
SCHEMBL3158927 0.80 PDE10A (0.40) PDE10ACA2
SCHEMBL2066634 0.80 CA2 (0.33) CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8148524-B2 Process for producing sulfonyl chloride compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-04-03 US disclosed
US-20090247748-A1 PROCESS FOR PRODUCING SULFONYL CHLORIDE COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-10-01 US disclosed
EP-1932846-A1 METHOD FOR PRODUCING SULFONYL CHLORIDE COMPOUND Sumitomo Chemical Company, Limited (JP) 2008-06-18 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090247748-A1 PROCESS FOR PRODUCING SULFONYL CHLORIDE COMPOUND SALL4, CLCN2, CLIC1 PDE10A 3486/4885CA2 176/4885CA12 1529/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.