SCHEMBL264810

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL17018447	0.80	ACHE (0.48)	FBP1ALDH1A1MAPTHPGDTSHR
	SCHEMBL1123827	0.79	BRD4 (0.46)	ADRB2FBP1BRD4FFAR2ALDH1A1
	SCHEMBL10618115	0.78	TSHR (0.40)	ALDH1A1TSHRMAPK1TDP1
	SCHEMBL18632149	0.78	L3MBTL1 (0.41)	FBP1ALDH1A1MAPTTDP1MEN1
	SCHEMBL27496184	0.78	HSD17B10 (0.52)	ALDH1A1MAPTTSHRMAPK1TDP1
	SCHEMBL4087041	0.78	ALDH1A1 (0.46)	ALDH1A1MAPTTSHRMAPK1TDP1
	SCHEMBL4543337	0.78	ESR1 (0.50)	FBP1MAPTTDP1LMNASLC6A2
	SCHEMBL12983360	0.78	CYP1A2 (0.39)	ALDH1A1MAPTHPGDTSHRLMNA
	SCHEMBL264411	0.77	KDM4E (0.45)	ALDH1A1MAPTTSHRTDP1LMNA
	SCHEMBL20680909	0.77	KDM4E (0.45)	ALDH1A1MAPTTSHRTDP1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.