Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | PLK1 | P53350 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.38 |
| ▸ | OXTR | P30559 | 1/20 | 0.38 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2068019 | 0.78 | MEN1 (0.38) | SMN1; SMN2KDM4EMAPTALDH1A1MEN1 | |
| SCHEMBL2068529 | 0.77 | CHRM2 (0.50) | KDM4EGAAALDH1A1MEN1KMT2A | |
| SCHEMBL5182578 | 0.77 | MEN1 (0.38) | SMN1; SMN2PLK1MAPTALDH1A1MEN1 | |
| SCHEMBL5181181 | 0.73 | SMN1; SMN2 (0.39) | SMN1; SMN2PLK1KDM4EMAPTNLRP3 | |
| SCHEMBL5012154 | 0.71 | KDM4E (0.53) | SMN1; SMN2PLK1KDM4EGAAMAPT | |
| SCHEMBL30493949 | 0.71 | KDM4E (0.53) | SMN1; SMN2PLK1KDM4EGAAMAPT | |
| SCHEMBL3617576 | 0.70 | L3MBTL1 (0.54) | SMN1; SMN2PLK1KDM4EGAAMAPT | |
| SCHEMBL9279836 | 0.70 | GAA (0.63) | SMN1; SMN2PLK1KDM4EGAAMAPT | |
| SCHEMBL8372045 | 0.70 | KDM4E (0.51) | SMN1; SMN2PLK1KDM4EGAAMAPT | |
| SCHEMBL6444346 | 0.68 | KDM4E (0.60) | SMN1; SMN2PLK1KDM4EGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7977332-B2 | Insecticidal N-(heteroarylalkyl)alkanediamine derivatives | FMC CORPORATION (US) | 2011-07-12 | — | — | US | disclosed |
| US-20110065710-A1 | Insecticidal N-(Heteroarylalkyl)Alkanediamine Derivatives | FMC CORPORATION | 2011-03-17 | — | — | US | disclosed |
| EP-1689231-A4 | INSECTICIDAL N-(HETEROARYLALKYL) ALKANEDIAMINE DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2007-11-14 | — | — | EP | disclosed |
| EP-1689231-A2 | INSECTICIDAL N-(HETEROARYLALKYL) ALKANEDIAMINE DERIVATIVES | FMC CORPORATION (US) | 2006-08-16 | — | — | EP | disclosed |
| WO-2005055715-A2 | INSECTICIDAL N-(HETEROARYLALKYL) ALKANEDIAMINE DERIVATIVES | FMC CORPORATION (US) | 2005-06-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110065710-A1 | Insecticidal N-(Heteroarylalkyl)Alkanediamine Derivatives | DDT, RABL6, ACHE | SMN1; SMN2 2602/4885PLK1 4560/4885KDM4E 1754/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.