Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.70 |
| ▸ | EP300 | Q09472 | 1/20 | 0.67 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.67 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.67 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.61 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.61 |
| ▸ | HSP90AA1 | P07900 | 7/20 | 0.60 |
| ▸ | CRHBP | P24387 | 1/20 | 0.60 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | G6PD | P11413 | 1/20 | 0.56 |
| ▸ | STAT3 | P40763 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | RRM1 | P23921 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18870843 | 0.93 | HKDC1 (0.67) | HKDC1EP300KAT2BKAT8KEAP1 | |
| SCHEMBL2069322 | 0.92 | KEAP1 (0.71) | HKDC1EP300KAT2BKAT8KEAP1 | |
| SCHEMBL18870850 | 0.85 | HKDC1 (0.60) | HKDC1EP300KAT2BKAT8KEAP1 | |
| SCHEMBL30238204 | 0.85 | KEAP1 (0.61) | HKDC1EP300KAT2BKAT8KEAP1 | |
| SCHEMBL18870854 | 0.84 | HKDC1 (0.62) | HKDC1EP300KAT2BKAT8KEAP1 | |
| SCHEMBL6295723 | 0.84 | CHEK1 (0.75) | HKDC1EP300KAT2BKAT8KEAP1 | |
| SCHEMBL16137361 | 0.83 | STAT3 (0.79) | HKDC1EP300KAT2BKAT8KEAP1 | |
| SCHEMBL3260797 | 0.82 | HKDC1 (1.00) | HKDC1EP300KAT2BKAT8KEAP1 | |
| SCHEMBL18838248 | 0.81 | HKDC1 (0.56) | HKDC1EP300KAT2BKAT8KEAP1 | |
| SCHEMBL18871298 | 0.81 | EP300 (0.59) | HKDC1EP300KAT2BKAT8KEAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7902207-B2 | Process for production of amines | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2011-03-08 | — | — | US | disclosed |
| US-20070142639-A1 | Process for production of amines | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2007-06-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070142639-A1 | Process for production of amines | SMS, CCNT1, PEAK1 | HKDC1 4375/4885EP300 3981/4885KAT2B 4368/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.