Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.33 |
| ▸ | MEN1 | O00255 | 4/20 | 0.32 |
| ▸ | MAPT | P10636 | 4/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.32 |
| ▸ | RELA | Q04206 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.31 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10031422 | 0.77 | NOS3 (0.36) | ALDH1A1KDM4EGLAL3MBTL1KMT2A | |
| SCHEMBL17859719 | 0.72 | ALDH1A1 (0.33) | ALDH1A1KDM4EKMT2AMEN1MAPT | |
| SCHEMBL29858016 | 0.68 | KMT2A (0.50) | ALDH1A1KDM4EGLAL3MBTL1KMT2A | |
| SCHEMBL25850101 | 0.68 | KMT2A (0.50) | ALDH1A1KDM4EGLAL3MBTL1KMT2A | |
| SCHEMBL22861519 | 0.68 | KMT2A (0.50) | ALDH1A1KDM4EGLAL3MBTL1KMT2A | |
| SCHEMBL17598901 | 0.67 | — | — | |
| SCHEMBL242949 | 0.66 | S100B (0.52) | ALDH1A1KDM4EGLAL3MBTL1KMT2A | |
| SCHEMBL13754812 | 0.66 | S100B (0.52) | ALDH1A1KDM4EGLAL3MBTL1KMT2A | |
| SCHEMBL242948 | 0.66 | S100B (0.52) | ALDH1A1KDM4EGLAL3MBTL1KMT2A | |
| SCHEMBL13035384 | 0.66 | NOS3 (0.39) | ALDH1A1KDM4EGLAL3MBTL1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3233803-B1 | PROCESS FOR THE PREPARATION OF A DIARYLTHIOHYDANTOIN COMPOUND | ARAGON PHARMACEUTICALS INC (US) | 2019-01-30 | — | — | EP | disclosed |