Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 2/20 | 0.36 |
| ▸ | NOS1 | P29475 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.34 |
| ▸ | MAPT | P10636 | 7/20 | 0.34 |
| ▸ | MEN1 | O00255 | 5/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | S100B | P04271 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.33 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10064354 | 0.84 | NOS1 (0.39) | NOS3NOS1KMT2AALDH1A1MAPT | |
| SCHEMBL13593168 | 0.82 | KMT2A (0.37) | NOS3NOS1KMT2AALDH1A1MAPT | |
| SCHEMBL10064564 | 0.78 | KMT2A (0.55) | KMT2AALDH1A1MAPTMEN1KDM4E | |
| SCHEMBL13790518 | 0.78 | KMT2A (0.55) | KMT2AALDH1A1MAPTMEN1KDM4E | |
| SCHEMBL20683237 | 0.77 | ALDH1A1 (0.37) | KMT2AALDH1A1MAPTMEN1KDM4E | |
| Hydrochloric Acid SCHEMBL3910252 | 0.77 | KMT2A (0.54) | KMT2AALDH1A1MAPTMEN1KDM4E | |
| SCHEMBL13035384 | 0.73 | NOS3 (0.39) | NOS3NOS1KMT2AALDH1A1MAPT | |
| SCHEMBL22861519 | 0.71 | KMT2A (0.50) | NOS3NOS1KMT2AALDH1A1MAPT | |
| SCHEMBL29858016 | 0.71 | KMT2A (0.50) | NOS3NOS1KMT2AALDH1A1MAPT | |
| SCHEMBL25850101 | 0.71 | KMT2A (0.50) | NOS3NOS1KMT2AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8110597-B2 | Radioactive isotope-labeled dye compound | FUJIFILM CORPORATION (JP) | 2012-02-07 | — | — | US | disclosed |
| US-20110263872-A1 | RADIOACTIVE ISOTOPE-LABELED DYE COMPOUND | FUJIFILM CORPORATION (JP) | 2011-10-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110263872-A1 | RADIOACTIVE ISOTOPE-LABELED DYE COMPOUND | IK, PRMT1, PRMT3 | NOS3 303/4885NOS1 282/4885KMT2A 1051/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.