Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | RAB9A | P51151 | 2/20 | 0.60 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | USP2 | O75604 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.50 |
| ▸ | CNR1 | P21554 | 1/20 | 0.48 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | HTR7 | P34969 | 1/20 | 0.47 |
| ▸ | CKS1B | P61024 | 1/20 | 0.47 |
| ▸ | SKP1 | P63208 | 1/20 | 0.47 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.47 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.44 |
| ▸ | NCF1 | P14598 | 1/20 | 0.44 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20684698 | 0.84 | MEN1 (0.56) | MEN1KMT2ARAB9ANPC1USP2 | |
| SCHEMBL12632064 | 0.80 | KDR (0.43) | MEN1KMT2ARAB9ANPC1SMN1; SMN2 | |
| SCHEMBL19272769 | 0.80 | MEN1 (0.50) | MEN1KMT2ARAB9ANPC1USP2 | |
| SCHEMBL18552370 | 0.79 | MEN1 (0.60) | MEN1KMT2ARAB9ANPC1USP2 | |
| SCHEMBL28853192 | 0.78 | TRPV3 (0.45) | — | |
| SCHEMBL5115896 | 0.78 | MEN1 (0.58) | MEN1KMT2ARAB9ANPC1USP2 | |
| SCHEMBL23110924 | 0.77 | HDAC6 (0.44) | TP53SMN1; SMN2CNR1 | |
| SCHEMBL58442 | 0.77 | MEN1 (1.00) | MEN1KMT2ARAB9ATP53SMN1; SMN2 | |
| SCHEMBL4271497 | 0.77 | NCF1 (0.52) | MEN1KMT2ARAB9ANPC1USP2 | |
| SCHEMBL29125638 | 0.76 | KDM4E (0.63) | RAB9ANPC1TP53PKMSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3133078-B1 | ORGANOMETALLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME | SAMSUNG ELECTRONICS CO LTD (KR) | 2019-01-30 | — | — | EP | disclosed |