Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV3 | Q8NET8 | 8/20 | 0.45 |
| ▸ | SCN9A | Q15858 | 5/20 | 0.43 |
| ▸ | KIF11 | P52732 | 5/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12632064 | 0.85 | KDR (0.43) | KIF11 | |
| SCHEMBL20684697 | 0.78 | MEN1 (0.60) | — | |
| SCHEMBL2615265 | 0.77 | CCR1 (0.54) | TRPV3SCN9AKIF11 | |
| SCHEMBL28881729 | 0.77 | TRPV3 (0.48) | TRPV3SCN9AKIF11 | |
| SCHEMBL28345610 | 0.77 | KIF11 (0.65) | TRPV3SCN9AKIF11 | |
| SCHEMBL30755399 | 0.75 | TRPV3 (0.47) | TRPV3SCN9AKIF11 | |
| SCHEMBL22337449 | 0.75 | NOTUM (0.47) | TRPV3SCN9AKIF11 | |
| SCHEMBL8612884 | 0.75 | SCN9A (0.47) | TRPV3SCN9AKIF11 | |
| SCHEMBL16538337 | 0.74 | SCN9A (0.46) | TRPV3SCN9AKIF11 | |
| SCHEMBL1800349 | 0.74 | ASIC3 (0.60) | TRPV3SCN9AKIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105143188-B | Novel sulfonamide TRPA1 receptor antagonists | 阿里奥制药有限公司 | 2017-11-28 | — | — | CN | disclosed |