Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.47 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.45 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.44 |
| ▸ | CPB2 | Q96IY4 | 7/20 | 0.42 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.41 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.41 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.41 |
| ▸ | NMT2 | O60551 | 1/20 | 0.40 |
| ▸ | NMT1 | P30419 | 1/20 | 0.40 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2068543 | 1.00 | SLC6A5 (0.47) | SLC6A5FOLH1NOD1CPB2ERAP2 | |
| SCHEMBL8540023 | 0.95 | SLC6A5 (0.51) | SLC6A5FOLH1NOD1CPB2ERAP2 | |
| SCHEMBL8540018 | 0.95 | SLC6A5 (0.51) | SLC6A5FOLH1NOD1CPB2ERAP2 | |
| SCHEMBL30880423 | 0.86 | GNAI3 (0.45) | SLC6A5FOLH1NOD1CPB2ERAP2 | |
| SCHEMBL29453813 | 0.86 | NOD1 (0.42) | SLC6A5FOLH1NOD1CPB2 | |
| SCHEMBL847122 | 0.85 | GNAI3 (0.44) | SLC6A5FOLH1NOD1CPB2ERAP2 | |
| SCHEMBL30753565 | 0.85 | NMT1 (0.54) | SLC6A5FOLH1NOD1CPB2ERAP2 | |
| SCHEMBL847121 | 0.85 | GNAI3 (0.44) | SLC6A5FOLH1NOD1CPB2ERAP2 | |
| SCHEMBL29674782 | 0.84 | SLC6A5 (0.69) | SLC6A5NOD1NMT2NMT1 | |
| SCHEMBL29429304 | 0.84 | SLC6A5 (0.69) | SLC6A5NOD1NMT2NMT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9733241-B2 | Detection of degradative enzymes and biomolecules in bodily fluids | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2017-08-15 | — | — | US | disclosed |
| US-20160169885-A1 | DETECTION OF DEGRADATIVE ENZYMES AND BIOMOLECULES IN BODILY FLUIDS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2016-06-16 | — | — | US | disclosed |
| US-9222119-B2 | Detection of degradative enzymes and biomolecules in bodily fluids | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2015-12-29 | — | — | US | disclosed |
| US-20150094449-A1 | DETECTION OF DEGRADATIVE ENZYMES AND BIOMOLECULES IN BODILY FLUIDS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2015-04-02 | — | — | US | disclosed |
| US-8940866-B2 | Detection of degradative enzymes and biomolecules in bodily fluids | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2015-01-27 | — | — | US | disclosed |
| US-20130281660-A1 | DETECTION OF DEGRADATIVE ANZYMES AND BIOMOLECULES IN BODILY FLUIDS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2013-10-24 | — | — | US | disclosed |
| US-8507218-B2 | Detection of degradative enzymes in bodily fluids | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2013-08-13 | — | — | US | disclosed |
| US-20110065127-A1 | Detection of Degradative Enzymes and Biomolecules in Bodily Fluids | The Regents of the University of California a Cali fornia corporation (US) | 2011-03-17 | — | — | US | disclosed |
| WO-2009100447-A2 | DETECTION OF DEGRADATIVE ENZYMES AND BIOMOLECULES IN BODILY FLUIDS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2009-08-13 | — | — | WO | disclosed |