Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | PRKDC | P78527 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19221922 | 0.87 | ABL1 (0.46) | ALDH1A1MEN1KMT2AMAPK1L3MBTL1 | |
| SCHEMBL29823053 | 0.87 | ABL1 (0.46) | ALDH1A1MEN1KMT2AMAPK1L3MBTL1 | |
| SCHEMBL20681329 | 0.86 | LMNA (0.47) | GAAALDH1A1LMNARAB9AMAPT | |
| SCHEMBL19222007 | 0.84 | PTK6 (0.48) | ALDH1A1RAB9AMAPTKDM4E | |
| SCHEMBL26577159 | 0.83 | ALDH1A1 (0.52) | GAAALDH1A1LMNAMAPTMEN1 | |
| SCHEMBL24891451 | 0.82 | ABL1 (0.39) | GAAALDH1A1PRKDC | |
| SCHEMBL20689782 | 0.82 | EGFR (0.52) | GAAALDH1A1MAPK1 | |
| SCHEMBL30518153 | 0.80 | ALDH1A1 (0.49) | GAAALDH1A1LMNARAB9AMAPT | |
| SCHEMBL13832429 | 0.78 | BRPF1 (0.45) | ALDH1A1MEN1KMT2AMAPK1L3MBTL1 | |
| SCHEMBL7141573 | 0.78 | PRKDC (0.44) | GAAALDH1A1LMNAMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3658547-B1 | PROCESS FOR PREPARING N-(5-(4-(4-FORMYL-3-PHENYL-1H-PYRAZOL-1-YL)PYRIMIDIN-2-YLAMINO)-4-METHOXY-2-MORPHOLINOPHENYL)ACRYLAMIDE | YUHAN CORP (KR) | 2023-08-16 | — | — | EP | claimed |
| US-20230322753-A1 | HETEROARYL DERIVATIVE, METHOD FOR PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS ACTIVE INGREDIENT | VORONOI INC. (KR) | 2023-10-12 | — | — | US | disclosed |
| US-20230322753-A1 | HETEROARYL DERIVATIVE, METHOD FOR PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS ACTIVE INGREDIENT | VORONOI INC. (KR) | 2023-10-12 | — | — | US | disclosed |
| EP-3658547-B1 | PROCESS FOR PREPARING N-(5-(4-(4-FORMYL-3-PHENYL-1H-PYRAZOL-1-YL)PYRIMIDIN-2-YLAMINO)-4-METHOXY-2-MORPHOLINOPHENYL)ACRYLAMIDE | YUHAN CORP (KR) | 2023-08-16 | — | — | EP | disclosed |
| EP-3658547-B1 | PROCESS FOR PREPARING N-(5-(4-(4-FORMYL-3-PHENYL-1H-PYRAZOL-1-YL)PYRIMIDIN-2-YLAMINO)-4-METHOXY-2-MORPHOLINOPHENYL)ACRYLAMIDE | YUHAN CORP (KR) | 2023-08-16 | — | — | EP | disclosed |
| CN-116194111-A | Heteroaryl derivatives, process for preparing the same, and pharmaceutical compositions containing the same as active ingredient | 株式会社沃若诺伊生物 | 2023-05-30 | — | — | CN | disclosed |
| WO-2022060196-A1 | HETEROARYL DERIVATIVE, METHOD FOR PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS ACTIVE INGREDIENT | 보로노이바이오 주식회사 | 2022-03-24 | — | — | WO | disclosed |
| US-11198684-B2 | Intermediates useful for the synthesis of a selective inhibitor against protein kinase and processes for preparing the same | YUHAN CORPORATION (KR) | 2021-12-14 | — | — | US | disclosed |
| US-20210155607-A1 | INTERMEDIATES USEFUL FOR THE SYNTHESIS OF A SELECTIVE INHIBITOR AGAINST PROTEIN KINASE AND PROCESSES FOR PREPARING THE SAME | YUHAN CORPORATION (KR) | 2021-05-27 | — | — | US | disclosed |
| WO-2019022487-A1 | INTERMEDIATES USEFUL FOR THE SYNTHESIS OF A SELECTIVE INHIBITOR AGAINST PROTEIN KINASE AND PROCESSES FOR PREPARING THE SAME | YUHAN CORPORATION (KR) | 2019-01-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210155607-A1 | INTERMEDIATES USEFUL FOR THE SYNTHESIS OF A SELECTIVE INHIBITOR AGAINST PROTEIN KINASE AND PROCESSES FOR PREPARING THE SAME | ERBB2, EGFR, MAP3K20 | GAA 2923/4885ALDH1A1 3633/4885LMNA 4347/4885 |
| US-11198684-B2 | Intermediates useful for the synthesis of a selective inhibitor against protein kinase and processes for preparing the same | ERBB2, EGFR, MAP3K20 | GAA 2923/4885ALDH1A1 3633/4885LMNA 4347/4885 |
| US-20230322753-A1 | HETEROARYL DERIVATIVE, METHOD FOR PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS ACTIVE INGREDIENT | ERBB4, ERBB2, ERBB3 | GAA 1944/4885ALDH1A1 2285/4885LMNA 4716/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.