Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.52 |
| ▸ | MAPT | P10636 | 9/20 | 0.48 |
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16668618 | 0.88 | SIRT6 (0.46) | ALDH1A1MAPTLMNASMN1; SMN2MAPK1 | |
| SCHEMBL29974407 | 0.88 | SIRT6 (0.46) | ALDH1A1MAPTLMNASMN1; SMN2MAPK1 | |
| SCHEMBL20680880 | 0.87 | ALDH1A1 (0.56) | ALDH1A1MAPTLMNASMN1; SMN2MAPK1 | |
| SCHEMBL19222008 | 0.85 | ABL1 (0.42) | ALDH1A1MAPTMAPK1NPSR1 | |
| SCHEMBL25497224 | 0.84 | PKM (0.38) | ALDH1A1MAPTLMNASMN1; SMN2MAPK1 | |
| SCHEMBL26027328 | 0.83 | MAPT (0.40) | ALDH1A1MAPTMAPK1PKMHTT | |
| SCHEMBL28836526 | 0.83 | ALDH1A1 (0.52) | ALDH1A1MAPTLMNASMN1; SMN2MAPK1 | |
| SCHEMBL20689783 | 0.83 | GAA (0.48) | ALDH1A1MAPTLMNASMN1; SMN2MAPK1 | |
| SCHEMBL21949289 | 0.82 | WDR5 (0.43) | ALDH1A1MAPTMAPK1NPSR1 | |
| SCHEMBL7143311 | 0.80 | ALDH1A1 (0.46) | ALDH1A1MAPTLMNAMAPK1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3658547-B1 | PROCESS FOR PREPARING N-(5-(4-(4-FORMYL-3-PHENYL-1H-PYRAZOL-1-YL)PYRIMIDIN-2-YLAMINO)-4-METHOXY-2-MORPHOLINOPHENYL)ACRYLAMIDE | YUHAN CORP (KR) | 2023-08-16 | — | — | EP | claimed |
| EP-3658547-B1 | PROCESS FOR PREPARING N-(5-(4-(4-FORMYL-3-PHENYL-1H-PYRAZOL-1-YL)PYRIMIDIN-2-YLAMINO)-4-METHOXY-2-MORPHOLINOPHENYL)ACRYLAMIDE | YUHAN CORP (KR) | 2023-08-16 | — | — | EP | disclosed |
| CN-116194111-A | Heteroaryl derivatives, process for preparing the same, and pharmaceutical compositions containing the same as active ingredient | 株式会社沃若诺伊生物 | 2023-05-30 | — | — | CN | disclosed |
| WO-2022060196-A1 | HETEROARYL DERIVATIVE, METHOD FOR PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS ACTIVE INGREDIENT | 보로노이바이오 주식회사 | 2022-03-24 | — | — | WO | disclosed |