SCHEMBL2069133

SCHEMBL2069133

Cc1ccc(N(c2ccc(C)cc2)C2(N(c3ccc(C)cc3)c3ccc(C)cc3)CCCCC2)cc1

nearest known ligand 0.45

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.41
TSHR P16473 1/20 0.41
KMT2A Q03164 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
POLB P06746 1/20 0.37
ACHE P22303 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
RAB9A P51151 3/20 0.34
HTR2B P41595 1/20 0.32
MAPT P10636 2/20 0.31
MCOLN3 Q8TDD5 1/20 0.31
CYP2C19 P33261 1/20 0.31
GFER P55789 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5031067 0.77 SLC6A2 (0.38) ALDH1A1KMT2APOLB
SCHEMBL11910224 0.75 CYP2C19 (0.38) ALDH1A1TSHRKMT2ASMN1; SMN2POLB
SCHEMBL8664027 0.74 OPRL1 (0.47)
SCHEMBL39661 0.69 ESR1 (0.48) ALDH1A1TSHRKMT2ASMN1; SMN2ACHE
SCHEMBL21168792 0.69 ESR1 (0.48) ALDH1A1TSHRKMT2ASMN1; SMN2ACHE
SCHEMBL12306231 0.69 ESR1 (0.48) ALDH1A1TSHRKMT2ASMN1; SMN2ACHE
SCHEMBL13879208 0.69 ESR1 (0.48) ALDH1A1TSHRKMT2ASMN1; SMN2ACHE
SCHEMBL5452904 0.69 ESR1 (0.48) ALDH1A1TSHRKMT2ASMN1; SMN2ACHE
SCHEMBL15165419 0.68 TSHR (0.35) ALDH1A1TSHRKMT2ASMN1; SMN2POLB
SCHEMBL75338 0.67 ESR1 (0.47) ALDH1A1TSHRKMT2ASMN1; SMN2ACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1698613-B1 Tetramine compound and organic electroluminescence element HODOGAYA CHEMICAL CO LTD (JP) 2013-05-01 EP disclosed
US-7902402-B2 N,N'-bis(4-diphenylaminobiphenyl-4'-yl)-N,N'-diphenyl-4,4''-diamino-p-terphenyl; EL element comprises an anode, a hole transport layer, a light emitting layer, an electron transport layer and a cathode laminated sequentially on a substrate; displays; provides high luminance at low applied voltage HODOGAYA CHEMICAL CO., LTD. (JP) 2011-03-08 US disclosed
US-7897816-B2 N,N'-bis(4-diphenylaminobiphenyl-4'-yl)-N,N'-diphenyl-4,4''-diamino-p-terphenyl; EL element comprises an anode, a hole transport layer, a light emitting layer, an electron transport layer and a cathode laminated sequentially on a substrate; displays; provides high luminance at low applied voltage HODOGAYA CHEMICAL CO., LTD. (JP) 2011-03-01 US disclosed
US-7807274-B2 N,N'-bis(4-diphenylaminobiphenyl-4'-yl)-N,N'-diphenyl-4,4''-diamino-p-terphenyl; EL element comprises an anode, a hole transport layer, a light emitting layer, an electron transport layer and a cathode laminated sequentially on a substrate; displays; provides high luminance at low applied voltage HODOGAYA CHEMICAL CO., LTD. (JP) 2010-10-05 US disclosed
US-20100174115-A1 TETRAMINE COMPOUND AND ORGANIC EL DEVICE HODOGAYA CHEMICAL CO., LTD. (JP) 2010-07-08 US disclosed
US-20100171080-A1 TETRAMINE COMPOUND AND ORGANIC EL DEVICE HODOGAYA CHEMICAL CO., LTD. (JP) 2010-07-08 US disclosed
US-20070149816-A1 N,N'-bis(4-diphenylaminobiphenyl-4'-yl)-N,N'-diphenyl-4,4''-diamino-p-terphenyl; EL element comprises an anode, a hole transport layer, a light emitting layer, an electron transport layer and a cathode laminated sequentially on a substrate; displays; provides high luminance at low applied voltage HODOGAYA CHEMICAL CO., LTD. (JP) 2007-06-28 US disclosed
EP-1698613-A1 TETRAMINE COMPOUND AND ORGANIC EL DEVICE Hodogaya Chemical Co., Ltd. (JP) 2006-09-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070149816-A1 N,N'-bis(4-diphenylaminobiphenyl-4'-yl)-N,N'-diphenyl-4,4''-diamino-p-terphenyl; EL element comprises an anode, a hole transport layer, a light emitting layer, an electron transport layer and a cathode laminated sequentially on a substrate; displays; provides high luminance at low applied voltage SLC6A19, TEAD4, RPL19 ALDH1A1 869/4885TSHR 3286/4885KMT2A 1741/4885
US-20100171080-A1 TETRAMINE COMPOUND AND ORGANIC EL DEVICE TTI1, ELF3, TERT ALDH1A1 759/4885TSHR 370/4885KMT2A 696/4885
US-20100174115-A1 TETRAMINE COMPOUND AND ORGANIC EL DEVICE TTI1, TERT, RIF1 ALDH1A1 505/4885TSHR 378/4885KMT2A 594/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.