Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | ALB | P02768 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.30 |
| ▸ | P2RY11 | Q96G91 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20692199 | 1.00 | ALDH1A1 (0.31) | ALDH1A1LMNAALBMAPK1P2RY1 | |
| SCHEMBL20691320 | 0.85 | NT5E (0.41) | LMNAP2RY1 | |
| SCHEMBL20692222 | 0.82 | ALDH1A1 (0.32) | ALDH1A1LMNAALBMAPK1 | |
| SCHEMBL20692011 | 0.81 | ALDH1A1 (0.37) | ALDH1A1LMNAALBMAPK1 | |
| SCHEMBL24680745 | 0.80 | SLC29A1 (0.32) | — | |
| SCHEMBL20691300 | 0.77 | FHIT (0.38) | P2RY1P2RY11 | |
| SCHEMBL20691945 | 0.72 | BCHE (0.50) | ALDH1A1MAPK1P2RY1P2RY11 | |
| SCHEMBL20691455 | 0.72 | BCHE (0.50) | ALDH1A1MAPK1P2RY1P2RY11 | |
| SCHEMBL24679905 | 0.71 | RNASEL (0.40) | P2RY1P2RY11 | |
| SCHEMBL22340256 | 0.67 | ALDH1A1 (0.39) | ALDH1A1LMNAALBMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019023459-A1 | CYCLIC DINUCLEOTIDES AS ANTICANCER AGENTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2019-01-31 | — | — | WO | disclosed |