Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 9/20 | 0.39 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 7/20 | 0.36 |
| ▸ | SLC6A9 | P48067 | 3/20 | 0.35 |
| ▸ | PPARD | Q03181 | 1/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | PTGES | O14684 | 3/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2069236 | 0.80 | PPARA (0.50) | SMN1; SMN2PPARAPPARGPPARDPTGDR2 | |
| SCHEMBL2821385 | 0.78 | PTGDR2 (0.44) | SMN1; SMN2PPARDPTGDR2ALDH1A1POLB | |
| SCHEMBL8935705 | 0.75 | SMN1; SMN2 (0.54) | SMN1; SMN2PPARALTB4RPPARGPPARD | |
| SCHEMBL8935703 | 0.75 | SMN1; SMN2 (0.54) | SMN1; SMN2PPARALTB4RPPARGPPARD | |
| SCHEMBL31698014 | 0.72 | SMN1; SMN2 (0.48) | SMN1; SMN2PPARALTB4RPPARGPPARD | |
| SCHEMBL28829280 | 0.72 | SMN1; SMN2 (0.48) | SMN1; SMN2PPARALTB4RPPARGPPARD | |
| SCHEMBL22771505 | 0.72 | ALDH1A1 (0.37) | SMN1; SMN2ALDH1A1POLBMAPK1MAPT | |
| SCHEMBL4817584 | 0.71 | SMN1; SMN2 (0.49) | SMN1; SMN2PPARAPPARGPPARDPTGDR2 | |
| SCHEMBL8935797 | 0.70 | PPARA (0.49) | SMN1; SMN2PPARALTB4RPPARGMAPT | |
| SCHEMBL1245341 | 0.70 | PPARA (0.49) | SMN1; SMN2PPARALTB4RPPARGMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7968723-B2 | Compounds, their preparation and use | HIGH POINT PHARMACEUTICALS, LLC (US) | 2011-06-28 | — | — | US | disclosed |