Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 1/20 | 0.35 |
| ▸ | MMP3 | P08254 | 1/20 | 0.35 |
| ▸ | NMUR2 | Q9GZQ4 | 2/20 | 0.33 |
| ▸ | NMUR1 | Q9HB89 | 2/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 6/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 6/20 | 0.33 |
| ▸ | ACE | P12821 | 2/20 | 0.32 |
| ▸ | GRB2 | P62993 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 2/20 | 0.32 |
| ▸ | EPHA2 | P29317 | 2/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | NRP1 | O14786 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24918881 | 0.88 | MMP1 (0.34) | MMP1MMP3NMUR2NMUR1ACE | |
| SCHEMBL22861995 | 0.84 | NRP1 (0.44) | NMUR2NMUR1OPRM1OPRK1GRB2 | |
| SCHEMBL21711187 | 0.77 | F2 (0.47) | MMP1MMP3OPRM1OPRK1GRB2 | |
| SCHEMBL31110301 | 0.77 | F2 (0.47) | MMP1MMP3OPRM1OPRK1GRB2 | |
| SCHEMBL9001262 | 0.76 | LMNA (0.38) | NMUR2NMUR1ACEGRB2 | |
| SCHEMBL30416412 | 0.75 | GRB2 (0.47) | NMUR2NMUR1OPRM1OPRK1GRB2 | |
| SCHEMBL29636207 | 0.75 | GRB2 (0.49) | NMUR2NMUR1OPRM1OPRK1GRB2 | |
| SCHEMBL29391363 | 0.74 | GRB2 (0.55) | NMUR2NMUR1OPRM1OPRK1GRB2 | |
| SCHEMBL13903017 | 0.73 | DPP4 (0.39) | NMUR2NMUR1GRB2DPP4 | |
| SCHEMBL15524993 | 0.73 | DPP4 (0.41) | OPRM1OPRK1GRB2DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019023501-A1 | UNIVERSAL ABT COMPOUNDS AND USES THEREOF | KLEO PHARMACEUTICALS, INC. (US) | 2019-01-31 | — | — | WO | disclosed |