Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 6/20 | 0.42 |
| ▸ | EYA3 | Q99504 | 3/20 | 0.41 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | APAF1 | O14727 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20695310 | 0.84 | ALDH1A1 (0.57) | ALDH1A1HPGDLMNARAB9ASMN1; SMN2 | |
| SCHEMBL24471013 | 0.77 | SLC26A4 (0.49) | LMNAKMT2AHTTTSHRMEN1 | |
| SCHEMBL20695245 | 0.76 | SLC26A4 (0.59) | LMNASMN1; SMN2KMT2AHTTTSHR | |
| SCHEMBL20695455 | 0.74 | MAPT (0.55) | ALDH1A1HPGDRAB9ASMN1; SMN2KMT2A | |
| SCHEMBL20708931 | 0.73 | NPC1 (0.58) | ALDH1A1HPGDRAB9ASMN1; SMN2KMT2A | |
| SCHEMBL20695422 | 0.73 | MCL1 (0.48) | ALDH1A1HPGDRAB9AKMT2AHTT | |
| SCHEMBL20695287 | 0.73 | PRNP (0.41) | CYP2C19CYP2C9ALDH1A1HPGDLMNA | |
| SCHEMBL20695398 | 0.72 | MCL1 (0.50) | ALDH1A1HPGDRAB9ASMN1; SMN2KMT2A | |
| SCHEMBL20695160 | 0.72 | CRBN (0.45) | CRBN | |
| SCHEMBL20695504 | 0.70 | HTT (0.54) | CRBNCYP2C9ALDH1A1HPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10610520-B2 | Heterocyclic compound | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2020-04-07 | — | — | US | disclosed |
| US-20190125728-A1 | HETEROCYCLIC COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2019-05-02 | — | — | US | disclosed |
| US-20190125728-A1 | HETEROCYCLIC COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2019-05-02 | — | — | US | disclosed |
| EP-3438109-A1 | HETEROCYCLIC COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2019-02-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190125728-A1 | HETEROCYCLIC COMPOUND | MAG, HTT, ACHE | CYP2C19 2900/4885EYA3 3032/4885CRBN 3810/4885 |
| US-10610520-B2 | Heterocyclic compound | MAG, HTT, ACHE | CYP2C19 2900/4885EYA3 3032/4885CRBN 3810/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.