Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC26A4 | O43511 | 5/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | CASP3 | P42574 | 1/20 | 0.48 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.48 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.48 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | ANO1 | Q5XXA6 | 4/20 | 0.45 |
| ▸ | MAOB | P27338 | 3/20 | 0.42 |
| ▸ | MAOA | P21397 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20695245 | 0.93 | SLC26A4 (0.59) | SLC26A4KMT2AMEN1LMNABLM | |
| SCHEMBL20695121 | 0.77 | CYP2C19 (0.42) | KMT2AMEN1LMNAHTTL3MBTL1 | |
| SCHEMBL20708937 | 0.76 | SLC26A4 (0.49) | SLC26A4KMT2AMEN1LMNABLM | |
| SCHEMBL24471001 | 0.75 | SLC26A4 (0.82) | SLC26A4KMT2AMEN1LMNABLM | |
| SCHEMBL29713104 | 0.75 | SLC26A4 (0.82) | SLC26A4KMT2AMEN1LMNABLM | |
| SCHEMBL24470733 | 0.74 | MAOB (0.40) | MAOBMAOAMAPTACHE | |
| SCHEMBL20695445 | 0.73 | SLC26A4 (0.50) | SLC26A4KMT2AMEN1MAPT | |
| SCHEMBL24470576 | 0.72 | CASP3 (0.69) | SLC26A4KMT2AMEN1LMNABLM | |
| SCHEMBL20708931 | 0.72 | NPC1 (0.58) | KMT2AMEN1HTTMAPTTSHR | |
| SCHEMBL24470590 | 0.71 | CASP3 (0.68) | SLC26A4KMT2AMEN1LMNABLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022112345-A1 | ARYL DERIVATIVES FOR TREATING TRPM3 MEDIATED DISORDERS | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2022-06-02 | — | — | WO | disclosed |