Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCKDK | O14874 | 2/20 | 0.52 |
| ▸ | MCL1 | Q07820 | 5/20 | 0.49 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.48 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | PRNP | P04156 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.37 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.36 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.36 |
| ▸ | RPA1 | P27694 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6026684 | 0.84 | STING1 (0.40) | BCKDKMCL1BCL2L1RXFP1STING1 | |
| SCHEMBL912067 | 0.79 | BCKDK (0.56) | BCKDKMCL1BCL2L1RXFP1STING1 | |
| SCHEMBL6025665 | 0.79 | BCKDK (0.56) | BCKDKMCL1BCL2L1RXFP1STING1 | |
| SCHEMBL694493 | 0.77 | BCKDK (0.57) | BCKDKMCL1BCL2L1RXFP1STING1 | |
| SCHEMBL6840187 | 0.77 | MCL1 (0.60) | BCKDKMCL1BCL2L1RXFP1STING1 | |
| SCHEMBL5224932 | 0.75 | STING1 (0.69) | BCKDKMCL1BCL2L1RXFP1STING1 | |
| SCHEMBL6840188 | 0.74 | MCL1 (0.60) | BCKDKMCL1BCL2L1RXFP1STING1 | |
| SCHEMBL20695240 | 0.73 | BCKDK (0.46) | BCKDKMCL1BCL2L1RXFP1MAPK1 | |
| SCHEMBL20695307 | 0.72 | MGLL (0.38) | ALDH1A1LMNA | |
| SCHEMBL20708724 | 0.72 | LMNA (0.34) | STING1HTTEPHX2KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10610520-B2 | Heterocyclic compound | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2020-04-07 | — | — | US | disclosed |
| US-20190125728-A1 | HETEROCYCLIC COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2019-05-02 | — | — | US | disclosed |
| EP-3438109-A1 | HETEROCYCLIC COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2019-02-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190125728-A1 | HETEROCYCLIC COMPOUND | MAG, HTT, ACHE | BCKDK 3150/4885MCL1 150/4885BCL2L1 40/4885 |
| US-10610520-B2 | Heterocyclic compound | MAG, HTT, ACHE | BCKDK 3150/4885MCL1 150/4885BCL2L1 40/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.