Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 3/20 | 0.53 |
| ▸ | BCR | P11274 | 3/20 | 0.53 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.53 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | CCR1 | P32246 | 1/20 | 0.43 |
| ▸ | CCR5 | P51681 | 1/20 | 0.43 |
| ▸ | CCR8 | P51685 | 1/20 | 0.43 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.43 |
| ▸ | KDM1A | O60341 | 1/20 | 0.43 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.42 |
| ▸ | AURKA | O14965 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20696576 | 0.91 | ABL1 (0.42) | ABL1BCRABCB1TGFBR1CYP1A2 | |
| SCHEMBL27911207 | 0.89 | KDM1A (0.51) | CYP1A2CYP2D6CYP19A1CYP2C9CYP2C19 | |
| SCHEMBL18573263 | 0.85 | CCR1 (0.53) | TGFBR1CYP1A2CYP2D6CYP19A1CYP2C9 | |
| SCHEMBL20696566 | 0.83 | ABL1 (0.46) | ABL1BCRABCB1TGFBR1CYP1A2 | |
| SCHEMBL20696577 | 0.82 | ABL1 (0.50) | ABL1BCRABCB1TGFBR1CYP1A2 | |
| SCHEMBL23956343 | 0.81 | CCR1 (0.53) | ABL1BCRABCB1TGFBR1CYP1A2 | |
| SCHEMBL20696579 | 0.80 | ABL1 (0.48) | ABL1BCRABCB1TGFBR1CYP1A2 | |
| SCHEMBL20696568 | 0.79 | ABL1 (0.47) | ABL1BCRABCB1MEN1KMT2A | |
| SCHEMBL20696569 | 0.78 | ALDH1A1 (0.62) | ABL1BCRABCB1CYP1A2CYP2D6 | |
| SCHEMBL8248415 | 0.77 | NPC1 (0.52) | ABL1BCRTGFBR1CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11535640-B2 | Metal complexes | MERCK PATENT GMBH (DE) | 2022-12-27 | — | — | US | disclosed |
| EP-3658564-B1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2021-05-19 | — | — | EP | disclosed |
| US-20200207794-A1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2020-07-02 | — | — | US | disclosed |
| WO-2019020538-A1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2019-01-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200207794-A1 | METAL COMPLEXES | IMMT, MCU, SOD1 | ABL1 2133/4885BCR 4438/4885ABCB1 3851/4885 |
| US-11535640-B2 | Metal complexes | IMMT, MCU, SOD1 | ABL1 2133/4885BCR 4438/4885ABCB1 3851/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.