Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.40 |
| ▸ | CES1 | P23141 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 5/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.39 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 6/20 | 0.38 |
| ▸ | HTT | P42858 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25876618 | 0.86 | KDM4E (0.44) | KDM4EALDH1A1CES2CES1LMNA | |
| SCHEMBL19155573 | 0.85 | CES2 (0.41) | KDM4EALDH1A1CES2CES1LMNA | |
| SCHEMBL19155631 | 0.84 | KDM4E (0.50) | KDM4EALDH1A1CES2CES1LMNA | |
| SCHEMBL16608093 | 0.83 | KDM4E (0.43) | KDM4EALDH1A1CES2CES1LMNA | |
| SCHEMBL20698005 | 0.83 | KDM4E (0.40) | KDM4EALDH1A1CES2CES1LMNA | |
| SCHEMBL23182121 | 0.81 | KDM4E (0.39) | KDM4EALDH1A1CES2CES1LMNA | |
| SCHEMBL23046369 | 0.78 | KDM4E (0.44) | KDM4EALDH1A1CES2CES1LMNA | |
| SCHEMBL25066770 | 0.78 | CES2 (0.38) | KDM4EALDH1A1CES2CES1LMNA | |
| SCHEMBL21953560 | 0.75 | KDM4E (0.48) | KDM4EALDH1A1CES2CES1LMNA | |
| SCHEMBL10465175 | 0.75 | ALDH1A1 (0.52) | KDM4EALDH1A1CES2CES1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230145668-A1 | MONOCARBONYL RUTHENIUM AND OSMIUM CATALYSTS | UNIV DEGLI STUDI UDINE (IT) | 2023-05-11 | — | — | US | disclosed |
| US-11577233-B2 | Monocarbonyl ruthenium and osmium catalysts | Universita' Delgi Studi Di Udine (IT) | 2023-02-14 | — | — | US | disclosed |
| US-20220168720-A1 | MONOCARBONYL RUTHENIUM AND OSMIUM CATALYSTS | UNIV DEGLI STUDI UDINE (IT) | 2022-06-02 | — | — | US | disclosed |
| WO-2021133903-A1 | ANALYTE SENSORS AND SENSING METHODS FEATURING LOW-POTENTIAL DETECTION | ABBOTT DIABETES CARE INC. (US) | 2021-07-01 | — | — | WO | disclosed |
| US-20190030522-A1 | MONOCARBONYL RUTHENIUM AND OSMIUM CATALYSTS | UNIVERSITA' DEGLI STUDI DI UDINE AND INNOVATION FACTORY S.R.L. (IT) | 2019-01-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230145668-A1 | MONOCARBONYL RUTHENIUM AND OSMIUM CATALYSTS | OTC, CBR3, IDH2 | KDM4E 1659/4885ALDH1A1 1605/4885CES2 3026/4885 |
| US-20220168720-A1 | MONOCARBONYL RUTHENIUM AND OSMIUM CATALYSTS | OTC, CBR3, IDH2 | KDM4E 1659/4885ALDH1A1 1605/4885CES2 3026/4885 |
| US-11577233-B2 | Monocarbonyl ruthenium and osmium catalysts | OTC, CBR3, IDH2 | KDM4E 1659/4885ALDH1A1 1605/4885CES2 3026/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.