Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 4/20 | 0.37 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.37 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | CTNNB1 | P35222 | 4/20 | 0.34 |
| ▸ | WNT3A | P56704 | 3/20 | 0.34 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19155573 | 0.82 | CES2 (0.41) | KDM4EALDH1A1RAB9AHTTSMN1; SMN2 | |
| SCHEMBL20697741 | 0.81 | KDM4E (0.43) | KDM4EALDH1A1RAB9AHTTSMN1; SMN2 | |
| SCHEMBL20698005 | 0.77 | KDM4E (0.40) | KDM4EALDH1A1RAB9AHTTSMN1; SMN2 | |
| SCHEMBL25066770 | 0.75 | CES2 (0.38) | KDM4EALDH1A1RAB9AHTTSMN1; SMN2 | |
| SCHEMBL25525738 | 0.70 | KDM4E (0.45) | KDM4EALDH1A1RAB9AHTTSMN1; SMN2 | |
| SCHEMBL20825179 | 0.69 | MAPK1 (0.50) | KDM4EALDH1A1RAB9ASMN1; SMN2CES2 | |
| SCHEMBL10465175 | 0.69 | ALDH1A1 (0.52) | KDM4EALDH1A1RAB9AHTTSMN1; SMN2 | |
| SCHEMBL18410851 | 0.69 | ALDH1A1 (0.52) | KDM4EALDH1A1RAB9AHTTSMN1; SMN2 | |
| SCHEMBL19154947 | 0.69 | MAPK1 (0.50) | KDM4EALDH1A1RAB9ASMN1; SMN2CES2 | |
| SCHEMBL27611283 | 0.69 | CES2 (0.45) | KDM4EALDH1A1RAB9AHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3411347-B1 | MONOCARBONYL RUTHENIUM AND OSMIUM CATALYSTS | UNIV DEGLI STUDI UDINE (IT) | 2021-03-31 | — | — | EP | disclosed |