Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 9/20 | 0.36 |
| ▸ | NPC1 | O15118 | 8/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.36 |
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.36 |
| ▸ | PKM | P14618 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.36 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20697741 | 0.83 | KDM4E (0.43) | KDM4EALDH1A1CES2CES1RAB9A | |
| SCHEMBL19155573 | 0.81 | CES2 (0.41) | KDM4EALDH1A1CES2CES1RAB9A | |
| SCHEMBL23182121 | 0.77 | KDM4E (0.39) | KDM4EALDH1A1CES2CES1RAB9A | |
| SCHEMBL25066770 | 0.74 | CES2 (0.38) | KDM4EALDH1A1CES2CES1RAB9A | |
| SCHEMBL10465175 | 0.72 | ALDH1A1 (0.52) | KDM4EALDH1A1CES2CES1RAB9A | |
| SCHEMBL18410851 | 0.72 | ALDH1A1 (0.52) | KDM4EALDH1A1CES2CES1RAB9A | |
| SCHEMBL23046369 | 0.71 | KDM4E (0.44) | KDM4EALDH1A1CES2CES1RAB9A | |
| SCHEMBL25876618 | 0.71 | KDM4E (0.44) | KDM4EALDH1A1CES2CES1RAB9A | |
| SCHEMBL25525738 | 0.69 | KDM4E (0.45) | KDM4EALDH1A1CES2CES1RAB9A | |
| SCHEMBL20825179 | 0.68 | MAPK1 (0.50) | KDM4EALDH1A1CES2CES1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190030522-A1 | MONOCARBONYL RUTHENIUM AND OSMIUM CATALYSTS | UNIVERSITA' DEGLI STUDI DI UDINE AND INNOVATION FACTORY S.R.L. (IT) | 2019-01-31 | — | — | US | disclosed |