Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.47 |
| ▸ | LMNA | P02545 | 5/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.47 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.47 |
| ▸ | ABHD5 | Q8WTS1 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.45 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.45 |
| ▸ | RELA | Q04206 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL600479 | 0.81 | ALDH1A1 (0.68) | MAPTALDH1A1LMNANPSR1HPGD | |
| SCHEMBL9330897 | 0.81 | ALDH1A1 (0.68) | MAPTALDH1A1LMNANPSR1HPGD | |
| SCHEMBL600478 | 0.81 | ALDH1A1 (0.68) | MAPTALDH1A1LMNANPSR1HPGD | |
| SCHEMBL6947763 | 0.80 | MAPT (0.62) | MAPTALDH1A1LMNANPSR1HPGD | |
| SCHEMBL22701981 | 0.80 | ALDH1A1 (0.47) | MAPTALDH1A1LMNANPSR1HPGD | |
| SCHEMBL6944654 | 0.80 | ALDH1A1 (0.47) | MAPTALDH1A1LMNANPSR1HPGD | |
| SCHEMBL6948401 | 0.80 | ALDH1A1 (0.67) | MAPTALDH1A1LMNANPSR1HPGD | |
| SCHEMBL6944659 | 0.80 | ALDH1A1 (0.47) | MAPTALDH1A1LMNANPSR1HPGD | |
| SCHEMBL6948405 | 0.80 | ALDH1A1 (0.67) | MAPTALDH1A1LMNANPSR1HPGD | |
| SCHEMBL6947760 | 0.80 | MAPT (0.62) | MAPTALDH1A1LMNANPSR1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11149034-B2 | Derivatives of luciferin and methods for their synthesis | UNIVERSITY OF CAPE TOWN (ZA) | 2021-10-19 | — | — | US | disclosed |
| US-20200331902-A1 | DERIVATIVES OF LUCIFERIN AND METHODS FOR THEIR SYNTHESIS | UNIVERSITY OF CAPE TOWN (ZA) | 2020-10-22 | — | — | US | disclosed |
| WO-2019021202-A1 | DERIVATIVES OF LUCIFERIN AND METHODS FOR THEIR SYNTHESIS | UNIVERSITY OF CAPE TOWN (ZA) | 2019-01-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200331902-A1 | DERIVATIVES OF LUCIFERIN AND METHODS FOR THEIR SYNTHESIS | GLB1, DBNL, GLO1 | MAPT 3781/4885ALDH1A1 747/4885LMNA 1623/4885 |
| US-11149034-B2 | Derivatives of luciferin and methods for their synthesis | GLB1, DBNL, GLO1 | MAPT 3781/4885ALDH1A1 747/4885LMNA 1623/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.