Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BPTF | Q12830 | 1/20 | 0.51 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.49 |
| ▸ | C1S | P09871 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | FAAH | O00519 | 1/20 | 0.47 |
| ▸ | MGLL | Q99685 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL255378 | 0.96 | ALDH1A1 (0.52) | BPTFALOX5C1SMEN1ALDH1A1 | |
| SCHEMBL30167608 | 0.96 | ALDH1A1 (0.52) | BPTFALOX5C1SMEN1ALDH1A1 | |
| SCHEMBL3159432 | 0.94 | SMN1; SMN2 (0.50) | BPTFALOX5C1SMEN1ALDH1A1 | |
| SCHEMBL20699709 | 0.91 | BPTF (0.54) | BPTFALOX5C1SMEN1ALDH1A1 | |
| SCHEMBL10373948 | 0.91 | BPTF (0.54) | BPTFALOX5C1SMEN1ALDH1A1 | |
| SCHEMBL29709387 | 0.88 | BPTF (0.46) | BPTFALOX5C1SMEN1ALDH1A1 | |
| SCHEMBL27955969 | 0.85 | KDM4E (0.47) | BPTFALOX5C1SMEN1ALDH1A1 | |
| SCHEMBL1267656 | 0.83 | BPTF (0.49) | BPTFALOX5C1SMEN1ALDH1A1 | |
| SCHEMBL456094 | 0.83 | SMN1; SMN2 (0.49) | BPTFALOX5C1SMEN1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL12817391 | 0.82 | HTR1A (0.59) | ALDH1A1MAPTHTTTP53HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116332929-A | 3-amido-beta-carboline compound, preparation method and application thereof | 中国科学院上海药物研究所 | 2023-06-27 | — | — | CN | disclosed |