Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 8/20 | 0.42 |
| ▸ | AHR | P35869 | 4/20 | 0.39 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.37 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 2/20 | 0.36 |
| ▸ | AR | P10275 | 2/20 | 0.35 |
| ▸ | TGM2 | P21980 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.33 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21966133 | 0.85 | AHR (0.39) | PGRAHRCHEK1LIMK1HTR2C | |
| SCHEMBL17027265 | 0.73 | BRD4 (0.56) | PGRBRD4ALDH1A1SMN1; SMN2 | |
| SCHEMBL17026771 | 0.73 | HTR2C (0.40) | PGRAHRCHEK1LIMK1HTR2C | |
| SCHEMBL21795060 | 0.71 | ALOX5 (0.44) | BRD4ALDH1A1CYP3A4 | |
| SCHEMBL17396556 | 0.69 | AHR (0.58) | AHRCHEK1LIMK1HTR2CTGM2 | |
| SCHEMBL11386072 | 0.67 | CHEK1 (0.55) | PGRAHRCHEK1LIMK1HTR2C | |
| SCHEMBL11858013 | 0.67 | TSHR (0.56) | AHRHTR2CALDH1A1LMNACYP1A2 | |
| SCHEMBL29561949 | 0.67 | TSHR (0.56) | AHRHTR2CALDH1A1LMNACYP1A2 | |
| SCHEMBL754751 | 0.66 | PGR (0.42) | PGRAHRTGM2CES1BRD4 | |
| SCHEMBL8629003 | 0.64 | NPC1 (0.49) | ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3438095-A1 | PYRIDAZINONE-TYPE COMPOUND OR SALT THEREOF, AND HERBICIDE COMPRISING SAME | Ishihara Sangyo Kaisha, Ltd. (JP) | 2019-02-06 | — | — | EP | disclosed |