Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P4HB | P07237 | 1/20 | 0.36 |
| ▸ | ACACB | O00763 | 2/20 | 0.35 |
| ▸ | DHFR | P00374 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | HTR3A | P46098 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | GFER | P55789 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2825593 | 0.84 | ACACB (0.35) | ACACBDHFRARALDH1A1MAPT | |
| SCHEMBL2827415 | 0.82 | GRM5 (0.44) | — | |
| SCHEMBL2070877 | 0.77 | PPARA (0.43) | ACACBALDH1A1MAPTACHEALOX15 | |
| SCHEMBL29438804 | 0.72 | TP53 (0.54) | ARALDH1A1MAPTALOX15ALOX12 | |
| SCHEMBL51244 | 0.72 | TP53 (0.54) | ARALDH1A1MAPTALOX15ALOX12 | |
| SCHEMBL2820981 | 0.72 | ERN1 (0.47) | — | |
| SCHEMBL2820963 | 0.72 | HSP90AA1 (0.32) | AR | |
| SCHEMBL18130105 | 0.71 | APP (0.62) | ACACBMAOBCHEK1ACHEAPP | |
| SCHEMBL16641175 | 0.71 | CA2 (0.54) | ACACBARALDH1A1ACHEHTR3A | |
| SCHEMBL10710607 | 0.69 | NR1H2 (0.58) | ARALDH1A1MAPTACHEALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1745003-B1 | NOVEL COMPOUNDS, THEIR PREPARATION AND USE | HIGH POINT PHARMACEUTICALS LLC (US) | 2010-10-27 | — | — | EP | claimed |