Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 7/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | STK17B | O94768 | 1/20 | 0.46 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20714669 | 0.87 | MAPT (0.43) | GAAMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL20714747 | 0.84 | MAPT (0.51) | GAAMAPTALDH1A1MAPK1TDP1 | |
| SCHEMBL4573754 | 0.83 | SUV39H2 (0.52) | GAAMAPTALDH1A1MAPK1TDP1 | |
| Bromide SCHEMBL11012696 | 0.82 | SUV39H2 (0.51) | GAAMAPTALDH1A1MAPK1TDP1 | |
| SCHEMBL11935576 | 0.81 | STK17B (0.57) | GAAMAPTALDH1A1MAPK1TDP1 | |
| SCHEMBL20715032 | 0.81 | MAPT (0.49) | GAAMAPTALDH1A1MAPK1TDP1 | |
| SCHEMBL7863619 | 0.81 | HTT (0.59) | GAAMAPTALDH1A1MAPK1TDP1 | |
| SCHEMBL5301519 | 0.81 | GAA (0.48) | GAAMAPTALDH1A1MAPK1TDP1 | |
| SCHEMBL20715031 | 0.80 | L3MBTL1 (0.50) | GAAMAPTALDH1A1TDP1MEN1 | |
| SCHEMBL11013534 | 0.79 | ALDH1A1 (0.55) | GAAMAPTALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019025153-A1 | USE OF SUBSTITUTED N-SULFONYL-N'-ARYL DIAMINOALKANES AND N-SULFONYL-N'-HETEROARYL DIAMINOALKANES OR SALTS THEREOF FOR INCREASING THE STRESS TOLERANCE IN PLANTS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2019-02-07 | — | — | WO | disclosed |