Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.51 |
| ▸ | GAA | P10253 | 5/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.51 |
| ▸ | CASP1 | P29466 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | ICMT | O60725 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20714854 | 0.86 | MAPT (0.44) | MAPTGAAKDM4EALDH1A1KMT2A | |
| SCHEMBL20715032 | 0.86 | MAPT (0.49) | MAPTGAAKDM4EALDH1A1KMT2A | |
| SCHEMBL20714770 | 0.84 | GAA (0.50) | MAPTGAAALDH1A1KMT2AMEN1 | |
| SCHEMBL20715031 | 0.84 | L3MBTL1 (0.50) | MAPTGAAKDM4EALDH1A1KMT2A | |
| SCHEMBL20714669 | 0.84 | MAPT (0.43) | MAPTGAAKDM4EALDH1A1KMT2A | |
| SCHEMBL3821707 | 0.83 | MAPT (0.53) | MAPTGAAKDM4EALDH1A1KMT2A | |
| SCHEMBL7838158 | 0.82 | MAPT (0.49) | MAPTGAAKDM4EALDH1A1KMT2A | |
| SCHEMBL10845913 | 0.81 | KDM4E (0.51) | MAPTGAAKDM4EALDH1A1KMT2A | |
| SCHEMBL8348474 | 0.81 | KDM4E (0.51) | MAPTGAAKDM4EALDH1A1KMT2A | |
| SCHEMBL20714825 | 0.80 | ALDH1A1 (0.55) | MAPTGAAKDM4EALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019025153-A1 | USE OF SUBSTITUTED N-SULFONYL-N'-ARYL DIAMINOALKANES AND N-SULFONYL-N'-HETEROARYL DIAMINOALKANES OR SALTS THEREOF FOR INCREASING THE STRESS TOLERANCE IN PLANTS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2019-02-07 | — | — | WO | disclosed |