Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 7/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | BCL6 | P41182 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14602131 | 0.83 | ALDH1A1 (0.47) | GAAMAPTALDH1A1MAPK1TDP1 | |
| SCHEMBL5302276 | 0.83 | ICMT (0.43) | MAPTMAPK1MEN1KMT2AHTT | |
| SCHEMBL20714770 | 0.81 | GAA (0.50) | GAAACHEMAPTALDH1A1MAPK1 | |
| SCHEMBL4573754 | 0.81 | SUV39H2 (0.52) | GAAACHEMAPTALDH1A1MAPK1 | |
| Bromide SCHEMBL11012696 | 0.79 | SUV39H2 (0.51) | GAAACHEMAPTALDH1A1MAPK1 | |
| SCHEMBL7863619 | 0.78 | HTT (0.59) | GAAMAPTALDH1A1MAPK1TDP1 | |
| SCHEMBL1581321 | 0.77 | PDE5A (0.52) | GAAMAPTALDH1A1MAPK1TDP1 | |
| SCHEMBL11935576 | 0.76 | STK17B (0.57) | GAAMAPTALDH1A1MAPK1TDP1 | |
| SCHEMBL8322708 | 0.74 | MAPT (0.57) | GAAACHEMAPTALDH1A1MEN1 | |
| SCHEMBL11013534 | 0.74 | ALDH1A1 (0.55) | GAAACHEMAPTALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007014273-A2 | SULFONAMIDES AS SELECTIVE ESTROGEN RECEPTOR MODULATORS | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2007-02-01 | — | — | WO | disclosed |
| US-20070021495-A1 | SULFONAMIDES AS SELECTIVE ESTROGEN RECEPTOR | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2007-01-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070021495-A1 | SULFONAMIDES AS SELECTIVE ESTROGEN RECEPTOR | ESR1, ESR2, GPER1 | GAA 3196/4885ACHE 2690/4885MAPT 4331/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.