SCHEMBL20715650

SCHEMBL20715650

N[C@@H](CCc1ccc(NC(=O)Nc2ccccc2)cc1)C(=O)O

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 6/20 0.58
CASP3 P42574 1/20 0.54
SENP7 Q9BQF6 1/20 0.54
SLC1A3 P43003 2/20 0.54
SLC1A2 P43004 2/20 0.54
SLC1A1 P43005 2/20 0.54
TP53 P04637 2/20 0.52
EPHX1 P07099 2/20 0.52
TSHR P16473 1/20 0.52
EPHX2 P34913 1/20 0.52
CDK9 P50750 1/20 0.52
SMN1; SMN2 Q16637 1/20 0.52
CLK4 Q9HAZ1 1/20 0.52
HTR1A P08908 1/20 0.51
DRD2 P14416 1/20 0.51
HIF1A Q16665 1/20 0.49
MAOA P21397 2/20 0.49
MAOB P27338 2/20 0.49
NPC1 O15118 2/20 0.48
RAB9A P51151 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19234901 0.84 SLC7A5 (0.66) LTA4HCASP3SENP7SLC1A3SLC1A2
SCHEMBL19234909 0.84 SLC7A5 (0.66) LTA4HCASP3SENP7SLC1A3SLC1A2
SCHEMBL6378833 0.82 LTA4H (0.48) LTA4HSLC1A3SLC1A2SLC1A1
Homophenylalanine SCHEMBL44312 0.82 ALPI (0.64) SLC1A3SLC1A2SLC1A1
Homophenylalanine SCHEMBL130567 0.82 ALPI (0.64) SLC1A3SLC1A2SLC1A1
Homophenylalanine SCHEMBL44311 0.82 ALPI (0.64) SLC1A3SLC1A2SLC1A1
Homophenylalanine SCHEMBL1078733 0.82 ALPI (0.64) SLC1A3SLC1A2SLC1A1
Homophenylalanine SCHEMBL1245414 0.80 ALPI (0.62) LTA4HSLC1A3SLC1A2SLC1A1
Homophenylalanine SCHEMBL2305748 0.80 ALPI (0.62) LTA4HSLC1A3SLC1A2SLC1A1
Homophenylalanine SCHEMBL28594537 0.80 ALPI (0.62) LTA4HSLC1A3SLC1A2SLC1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11279732-B2 Somatostatin receptor antagonist compounds and methods of using the same CDRD VENTURES INC. (CA) 2022-03-22 US disclosed
US-20190040102-A1 SOMATOSTATIN RECEPTOR ANTAGONIST COMPOUNDS AND METHODS OF USING THE SAME CDRD VENTURES INC. (CA) 2019-02-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11279732-B2 Somatostatin receptor antagonist compounds and methods of using the same GPR119, SSTR5, SSTR2 LTA4H 2077/4885CASP3 2194/4885SENP7 2681/4885
US-20190040102-A1 SOMATOSTATIN RECEPTOR ANTAGONIST COMPOUNDS AND METHODS OF USING THE SAME GPR119, SSTR5, SSTR2 LTA4H 2077/4885CASP3 2194/4885SENP7 2681/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.