Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 2/20 | 0.51 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 7/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.43 |
| ▸ | INSR | P06213 | 3/20 | 0.42 |
| ▸ | IGF1R | P08069 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20718359 | 0.88 | INSR (0.46) | ADRB2ADRB1MAPTALDH1A1NPSR1 | |
| SCHEMBL20718600 | 0.84 | ADRB2 (0.52) | ADRB2ADRB1MAPTALDH1A1NPSR1 | |
| SCHEMBL20718562 | 0.79 | ADRB2 (0.46) | ADRB2ADRB1MAPTALDH1A1NPSR1 | |
| SCHEMBL20718568 | 0.74 | ADRB2 (0.46) | ADRB2ADRB1MAPTALDH1A1NPSR1 | |
| SCHEMBL20718002 | 0.73 | MAPT (0.58) | ADRB2ADRB1MAPTALDH1A1NPSR1 | |
| SCHEMBL20718569 | 0.72 | INSR (0.49) | ADRB2ADRB1MAPTALDH1A1NPSR1 | |
| SCHEMBL20718563 | 0.72 | KDM4E (0.52) | ADRB2ADRB1MAPTALDH1A1NPSR1 | |
| SCHEMBL20718363 | 0.67 | INSR (0.49) | MAPTALDH1A1NPSR1POLBLMNA | |
| SCHEMBL1728691 | 0.66 | MAPT (0.64) | MAPTALDH1A1NPSR1HPGDPOLB | |
| SCHEMBL11236567 | 0.66 | HPGD (0.78) | MAPTALDH1A1NPSR1HPGDPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019025595-A1 | SELECTIVE LIGANDS FOR TAU AGGREGATES | KARIN & STEN MORTSTEDT CBD SOLUTIONS AB (SE) | 2019-02-07 | — | — | WO | disclosed |