Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.58 |
| ▸ | MEN1 | O00255 | 8/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.58 |
| ▸ | RAB9A | P51151 | 6/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | PKM | P14618 | 2/20 | 0.58 |
| ▸ | NPC1 | O15118 | 4/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.44 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.44 |
| ▸ | INSR | P06213 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 6/20 | 0.39 |
| ▸ | HPGD | P15428 | 4/20 | 0.39 |
| ▸ | PSMD14 | O00487 | 3/20 | 0.39 |
| ▸ | PTPN22 | Q9Y2R2 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20718001 | 0.79 | MAPT (0.55) | MAPTMEN1KMT2AALDH1A1RAB9A | |
| SCHEMBL20718562 | 0.76 | ADRB2 (0.46) | MAPTMEN1KMT2AALDH1A1RAB9A | |
| SCHEMBL20718600 | 0.76 | ADRB2 (0.52) | MAPTMEN1KMT2AALDH1A1RAB9A | |
| SCHEMBL20718568 | 0.76 | ADRB2 (0.46) | MAPTMEN1KMT2AALDH1A1RAB9A | |
| SCHEMBL10025480 | 0.74 | RAB9A (1.00) | MAPTMEN1KMT2AALDH1A1RAB9A | |
| SCHEMBL20718564 | 0.73 | ADRB2 (0.51) | MAPTMEN1KMT2AALDH1A1RAB9A | |
| SCHEMBL20718563 | 0.71 | KDM4E (0.52) | MAPTMEN1KMT2AALDH1A1RAB9A | |
| SCHEMBL12942446 | 0.70 | KMT2A (0.53) | MAPTMEN1KMT2AALDH1A1RAB9A | |
| SCHEMBL16160291 | 0.67 | RAB9A (0.62) | MAPTMEN1KMT2AALDH1A1RAB9A | |
| SCHEMBL20718458 | 0.66 | MAPT (0.51) | MAPTMEN1KMT2AALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019025595-A1 | SELECTIVE LIGANDS FOR TAU AGGREGATES | KARIN & STEN MORTSTEDT CBD SOLUTIONS AB (SE) | 2019-02-07 | — | — | WO | disclosed |