SCHEMBL20719587

SCHEMBL20719587

CC(C)(C)OC(=O)NCc1ccc(CC(=O)O)cn1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.46
RORC P51449 3/20 0.45
NAMPT P43490 2/20 0.44
GABRP O00591 1/20 0.43
GABRD O14764 1/20 0.43
GABRA1 P14867 1/20 0.43
GABRB1 P18505 1/20 0.43
GABRG2 P18507 1/20 0.43
GABRB3 P28472 1/20 0.43
GABRA5 P31644 1/20 0.43
GABRA3 P34903 1/20 0.43
GABRA2 P47869 1/20 0.43
GABRB2 P47870 1/20 0.43
GABRA4 P48169 1/20 0.43
GABRE P78334 1/20 0.43
GABRA6 Q16445 1/20 0.43
GABRG1 Q8N1C3 1/20 0.43
GABRG3 Q99928 1/20 0.43
GABRQ Q9UN88 1/20 0.43
P4HTM Q9NXG6 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12184770 0.86 L3MBTL1 (0.48) L3MBTL1NAMPTHDAC1DYRK1ACA12
SCHEMBL13707768 0.83 L3MBTL1 (0.46) L3MBTL1NAMPTGLSHDAC1DYRK1A
SCHEMBL1244728 0.82 EPHX2 (0.56) L3MBTL1RORCNAMPTGLSHDAC1
SCHEMBL2841433 0.82 GABRP (0.46) L3MBTL1NAMPTGABRPGABRDGABRA1
SCHEMBL1244524 0.81 NAMPT (0.46) L3MBTL1NAMPTP4HTMHDAC1CA12
SCHEMBL2586887 0.81 L3MBTL1 (0.54) L3MBTL1NAMPTHDAC1DYRK1ACA1
SCHEMBL30006337 0.81 L3MBTL1 (0.54) L3MBTL1NAMPTHDAC1DYRK1ACA1
SCHEMBL6369161 0.81 L3MBTL1 (0.44) L3MBTL1NAMPTGLSDYRK1ACA12
SCHEMBL6376889 0.81 L3MBTL1 (0.44) L3MBTL1NAMPTGLSDYRK1ACA12
SCHEMBL30385608 0.81 MEN1 (0.53) NAMPTHDAC1MAPTTDP1NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3447058-B1 NOVEL BROAD-SPECTRUM BETA-LACTAMASE INHIBITOR WUHAN VISION PHARMACEUTICAL TECH CO LTD (CN) 2023-10-11 EP disclosed
US-10479805-B2 Beta-lactamase inhibitor WUHAN VISION PHARMACEUTICAL TECHNOLOGY CO., LTD. (CN) 2019-11-19 US disclosed
US-20190048027-A1 BETA-LACTAMASE INHIBITOR WUHAN VISION PHARMACEUTICAL TECHNOLOGY CO., LTD. (CN) 2019-02-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190048027-A1 BETA-LACTAMASE INHIBITOR ALPI, MGAM, LCT L3MBTL1 391/4885RORC 2902/4885NAMPT 949/4885
US-10479805-B2 Beta-lactamase inhibitor ALPI, MGAM, LCT L3MBTL1 391/4885RORC 2902/4885NAMPT 949/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.