SCHEMBL20719962

SCHEMBL20719962

NCc1ccc(CN)c(S(=O)(=O)O)c1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 3/20 0.39
CA2 P00918 3/20 0.39
CA9 Q16790 3/20 0.39
CA12 O43570 2/20 0.39
CA4 P22748 2/20 0.39
CA6 P23280 2/20 0.39
CA5A P35218 2/20 0.39
CA7 P43166 2/20 0.39
CA14 Q9ULX7 2/20 0.39
CA5B Q9Y2D0 2/20 0.39
MAPT P10636 1/20 0.38
PSIP1 O75475 1/20 0.37
KDM4E B2RXH2 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
ABAT P80404 1/20 0.35
PNMT P11086 1/20 0.35
ENPP2 Q13822 1/20 0.35
POLB P06746 1/20 0.35
RECQL P46063 1/20 0.35
ESR2 Q92731 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29384212 0.83 CA1 (0.42) CA1CA2CA9CA12CA4
Potassium SCHEMBL29387211 0.83 CA1 (0.38) CA1CA2CA9CA12CA4
SCHEMBL7718118 0.81 RAPGEF4 (0.49) MAPTKDM4EPOLBRECQLGAA
SCHEMBL431618 0.81 ALDH1A1 (0.44) CA1CA2CA9CA12CA4
SCHEMBL8074965 0.81 CTDSP1 (0.43) CA1CA2CA9CA12CA4
SCHEMBL1805251 0.79 ALDH1A1 (0.40) CA1CA2CA9MAPTKDM4E
SCHEMBL1807106 0.79 CYP2A6 (0.39) CA1CA2CA9CA12MAPT
SCHEMBL1803020 0.79 POLB (0.54) CA1CA2CA9CA12CA4
SCHEMBL8030396 0.77 CA2 (0.39) CA1CA2CA9CA12CA4
SCHEMBL24002358 0.77 CDC25B (0.50) CA1CA2CA9CA12CA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11091646-B2 Luminescent squaraine rotaxane compounds SETA BIOMEDICALS, LLC (US) 2021-08-17 US disclosed
US-11091646-B2 Luminescent squaraine rotaxane compounds SETA BIOMEDICALS, LLC (US) 2021-08-17 US disclosed
US-20200199369-A9 LUMINESCENT SQUARAINE ROTAXANE COMPOUNDS SETA BIOMEDICALS, LLC 2020-06-25 US disclosed
US-20200199369-A9 LUMINESCENT SQUARAINE ROTAXANE COMPOUNDS SETA BIOMEDICALS, LLC 2020-06-25 US disclosed
US-20190048196-A1 LUMINESCENT SQUARAINE ROTAXANE COMPOUNDS SETA BIOMEDICALS LLC (US) 2019-02-14 US disclosed
US-20190048196-A1 LUMINESCENT SQUARAINE ROTAXANE COMPOUNDS SETA BIOMEDICALS LLC (US) 2019-02-14 US disclosed