Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.44 |
| ▸ | CASP6 | P55212 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | NT5E | P21589 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 3/20 | 0.40 |
| ▸ | CA2 | P00918 | 3/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | CA7 | P43166 | 2/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TIMP3 | P35625 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | SUMO2 | P61956 | 1/20 | 0.35 |
| ▸ | SUMO1 | P63165 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1807072 | 0.85 | ALDH1A1 (0.44) | ALDH1A1HSD17B10CASP6CYP2C9CYP2C19 | |
| SCHEMBL9154391 | 0.85 | ALDH1A1 (0.44) | ALDH1A1HSD17B10CASP6CYP2C9CYP2C19 | |
| SCHEMBL9514998 | 0.83 | CA2 (0.49) | ALDH1A1CA2 | |
| SCHEMBL1806781 | 0.82 | ALDH1A1 (0.41) | ALDH1A1HSD17B10CASP6CYP2C9CYP2C19 | |
| SCHEMBL1806779 | 0.82 | ALDH1A1 (0.41) | ALDH1A1HSD17B10CASP6CYP2C9CYP2C19 | |
| SCHEMBL5115210 | 0.82 | ALDH1A1 (0.41) | ALDH1A1HSD17B10CASP6CYP2C9CYP2C19 | |
| SCHEMBL1805939 | 0.82 | CA2 (0.42) | ALDH1A1HSD17B10CASP6CYP2C9CYP2C19 | |
| SCHEMBL1804515 | 0.81 | CA2 (0.41) | ALDH1A1HSD17B10CASP6CYP2C9CYP2C19 | |
| SCHEMBL20719962 | 0.81 | CA1 (0.39) | CA1CA2CA12CA7CA14 | |
| SCHEMBL7718118 | 0.81 | RAPGEF4 (0.49) | ALDH1A1HSD17B10CASP6CYP2C9TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2596065-B1 | LUMINESCENT DYES WITH A WATER-SOLUBLE INTRAMOLECULAR BRIDGE AND THEIR BIOLOGICAL CONJUGATES | BECTON DICKINSON CO (US) | 2018-03-07 | — | — | EP | disclosed |
| US-8623324-B2 | Luminescent dyes with a water-soluble intramolecular bridge and their biological conjugates | AAT BIOQUEST INC. (US) | 2014-01-07 | — | — | US | disclosed |
| EP-2596065-A2 | LUMINESCENT DYES WITH A WATER-SOLUBLE INTRAMOLECULAR BRIDGE AND THEIR BIOLOGICAL CONJUGATES | Becton, Dickinson and Company (US) | 2013-05-29 | — | — | EP | disclosed |
| US-8404036-B2 | Water-soluble near-infrared absorbing coloring matters and aqueous inks containing same | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2013-03-26 | — | — | US | disclosed |
| US-20120183954-A1 | LUMINESCENT DYES WITH A WATER-SOLUBLE INTRAMOLECULAR BRIDGE AND THEIR BIOLOGICAL CONJUGATES | AAT BIOQUEST, INC. (US) | 2012-07-19 | — | — | US | disclosed |
| WO-2012012595-A2 | LUMINESCENT DYES WITH A WATER-SOLUBLE INTRAMOLECULAR BRIDGE AND THEIR BIOLOGICAL CONJUGATES | BECTON, DICKINSON AND COMPANY (US) | 2012-01-26 | — | — | WO | disclosed |
| US-20110123784-A1 | WATER-SOLUBLE NEAR-INFRARED ABSORBING COLORING MATTERS AND AQUEOUS INKS CONTAINING SAME | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2011-05-26 | — | — | US | disclosed |
| US-4317893-A | ADDITON COPOLYMER CONTAINING ANHYDRIDE GROUPS MODIFIED BY ANIONIC GROUP-CONTAINING AMINE; STABILITY | MOBIL OIL CORPORATION (US) | 1982-03-02 | — | — | US | disclosed |
| US-4284517-A | Oil recovery by waterflooding employing anionic polymeric surfactants | MOBIL OIL CORPORATION (US) | 1981-08-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120183954-A1 | LUMINESCENT DYES WITH A WATER-SOLUBLE INTRAMOLECULAR BRIDGE AND THEIR BIOLOGICAL CONJUGATES | CD44, HLCS, GUSB | ALDH1A1 407/4885HSD17B10 2414/4885CASP6 3467/4885 |
| US-20110123784-A1 | WATER-SOLUBLE NEAR-INFRARED ABSORBING COLORING MATTERS AND AQUEOUS INKS CONTAINING SAME | IK, RB1, COL1A1 | ALDH1A1 218/4885HSD17B10 2848/4885CASP6 4737/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.