SCHEMBL20721986

SCHEMBL20721986

CC(=O)C(C)(C)C(=O)/C=C/N(C)C

nearest known ligand 0.56

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.56
RECQL P46063 2/20 0.35
MAPT P10636 5/20 0.33
CYP1A2 P05177 2/20 0.33
CYP2C19 P33261 2/20 0.33
HPGD P15428 2/20 0.33
HTT P42858 2/20 0.33
LMNA P02545 2/20 0.33
RAB9A P51151 2/20 0.33
ALOX12 P18054 1/20 0.33
ALDH1A1 P00352 6/20 0.32
GAA P10253 3/20 0.32
SMN1; SMN2 Q16637 2/20 0.32
POLB P06746 2/20 0.32
KDM4E B2RXH2 3/20 0.31
KMT2A Q03164 1/20 0.31
NPC1 O15118 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13221154 0.88 TDP1 (0.62) TDP1RECQLMAPTCYP1A2CYP2C19
SCHEMBL20721914 0.83 TDP1 (0.52) TDP1RECQLMAPTCYP1A2CYP2C19
SCHEMBL28926873 0.82 TDP1 (0.56) TDP1RECQLMAPTCYP1A2CYP2C19
SCHEMBL6977513 0.78 TDP1 (0.62) TDP1RECQLMAPTCYP1A2CYP2C19
SCHEMBL678566 0.78 TDP1 (0.62) TDP1RECQLMAPTCYP1A2CYP2C19
SCHEMBL24759814 0.77 TDP1 (0.50) TDP1RECQLMAPTCYP1A2CYP2C19
SCHEMBL17361336 0.77 TDP1 (0.50) TDP1RECQLMAPTCYP1A2CYP2C19
SCHEMBL17361335 0.77 TDP1 (0.50) TDP1RECQLMAPTCYP1A2CYP2C19
SCHEMBL19183375 0.71 TDP1 (1.00) TDP1RECQLMAPTCYP1A2CYP2C19
SCHEMBL3514654 0.71 TDP1 (0.60) TDP1RECQLMAPTCYP1A2CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240090312-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2024-03-14 US disclosed
US-11744142-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-08-29 US disclosed
US-11744142-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-08-29 US disclosed
US-11744142-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-08-29 US disclosed
EP-3783006-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES Universal Display Corporation (US) 2021-02-24 EP disclosed
EP-3444258-B1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORP (US) 2020-07-01 EP disclosed
EP-3444258-A2 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES Universal Display Corporation (US) 2019-02-20 EP disclosed
EP-3444258-A2 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES Universal Display Corporation (US) 2019-02-20 EP disclosed
US-20190051845-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2019-02-14 US disclosed
US-20190051845-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2019-02-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11744142-B2 Organic electroluminescent materials and devices TLL1, TLL2, ALPL TDP1 1375/4885RECQL 1079/4885MAPT 2307/4885
US-20240090312-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES TLL1, TLL2, ALPL TDP1 1375/4885RECQL 1079/4885MAPT 2307/4885
US-20190051845-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES TLL1, TLL2, ALPL TDP1 1375/4885RECQL 1079/4885MAPT 2307/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.